Intravital microscopy: Imaging host-parasite interactions in the brain
Intravital fluorescence microscopy (IVM) is a powerful technique for imaging multiple organs, including the brain of living mice and rats. It enables the direct visualisation of cells in situ providing a real-life view of biological processes that in vitro systems cannot. In addition, to the technol...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
04 March 2019
|
| In: |
Cellular microbiology
Year: 2019, Volume: 21, Issue: 5, Pages: 1-11 |
| ISSN: | 1462-5822 |
| DOI: | 10.1111/cmi.13024 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1111/cmi.13024 Verlag, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/cmi.13024 |
| Author Notes: | Mariana De Niz, Adéla Nacer, Friedrich Frischknecht |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1665671750 | ||
| 003 | DE-627 | ||
| 005 | 20230427160218.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 190515s2019 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1111/cmi.13024 |2 doi | |
| 035 | |a (DE-627)1665671750 | ||
| 035 | |a (DE-599)KXP1665671750 | ||
| 035 | |a (OCoLC)1341224567 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Niz, Mariana De |d 1988- |e VerfasserIn |0 (DE-588)1103704567 |0 (DE-627)861497465 |0 (DE-576)470745843 |4 aut | |
| 245 | 1 | 0 | |a Intravital microscopy |b Imaging host-parasite interactions in the brain |c Mariana De Niz, Adéla Nacer, Friedrich Frischknecht |
| 264 | 1 | |c 04 March 2019 | |
| 300 | |a 11 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 15.05.2019 | ||
| 520 | |a Intravital fluorescence microscopy (IVM) is a powerful technique for imaging multiple organs, including the brain of living mice and rats. It enables the direct visualisation of cells in situ providing a real-life view of biological processes that in vitro systems cannot. In addition, to the technological advances in microscopy over the last decade, there have been supporting innovations in data storage and analytical packages that enable the visualisation and analysis of large data sets. Here, we review the advantages and limitations of techniques predominantly used for brain IVM, including thinned skull windows, open skull cortical windows, and a miniaturised optical system based on microendoscopic probes that can be inserted into deep tissues. Further, we explore the relevance of these techniques for the field of parasitology. Several protozoan infections are associated with neurological symptoms including Plasmodium spp., Toxoplasma spp., and Trypanosoma spp. IVM has led to crucial findings on these parasite species, which are discussed in detail in this review. | ||
| 650 | 4 | |a brain | |
| 650 | 4 | |a host-pathogen interactions | |
| 650 | 4 | |a Infection | |
| 650 | 4 | |a intravital microscopy | |
| 650 | 4 | |a parasitology | |
| 700 | 1 | |a Nacer, Adéla |e VerfasserIn |0 (DE-588)1186156007 |0 (DE-627)1665674377 |4 aut | |
| 700 | 1 | |a Frischknecht, Friedrich |d 1968- |e VerfasserIn |0 (DE-588)122362160 |0 (DE-627)705878392 |0 (DE-576)293237298 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Cellular microbiology |d [Hoboken, NJ] : Wiley, 1999 |g 21(2019,5) Artikel-Nummer e13024, 11 Seiten |h Online-Ressource |w (DE-627)320599493 |w (DE-600)2019990-9 |w (DE-576)091140889 |x 1462-5822 |7 nnas |a Intravital microscopy Imaging host-parasite interactions in the brain |
| 773 | 1 | 8 | |g volume:21 |g year:2019 |g number:5 |g pages:1-11 |g extent:11 |a Intravital microscopy Imaging host-parasite interactions in the brain |
| 856 | 4 | 0 | |u https://doi.org/10.1111/cmi.13024 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/abs/10.1111/cmi.13024 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20190515 | ||
| 993 | |a Article | ||
| 994 | |a 2019 | ||
| 998 | |g 122362160 |a Frischknecht, Friedrich |m 122362160:Frischknecht, Friedrich |d 910000 |d 911700 |e 910000PF122362160 |e 911700PF122362160 |k 0/910000/ |k 1/910000/911700/ |p 3 |y j | ||
| 999 | |a KXP-PPN1665671750 |e 3475880393 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"note":["Gesehen am 15.05.2019"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"recId":"1665671750","language":["eng"],"title":[{"subtitle":"Imaging host-parasite interactions in the brain","title":"Intravital microscopy","title_sort":"Intravital microscopy"}],"person":[{"role":"aut","roleDisplay":"VerfasserIn","display":"Niz, Mariana De","given":"Mariana De","family":"Niz"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Nacer, Adéla","given":"Adéla","family":"Nacer"},{"family":"Frischknecht","given":"Friedrich","display":"Frischknecht, Friedrich","roleDisplay":"VerfasserIn","role":"aut"}],"physDesc":[{"extent":"11 S."}],"relHost":[{"id":{"issn":["1462-5822"],"zdb":["2019990-9"],"eki":["320599493"],"doi":["10.1111/(ISSN)1462-5822"]},"origin":[{"publisherPlace":"[Hoboken, NJ] ; Oxford ; Oxford [u.a.] ; Oxford [u.a.] ; London","dateIssuedKey":"2024","publisher":"Wiley ; Blackwell Science ; Blackwell ; Wiley-Blackwell ; Hindawi Limited","dateIssuedDisp":"2024-"}],"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title":"Cellular microbiology","title_sort":"Cellular microbiology"}],"recId":"320599493","language":["eng"],"note":["Gesehen am 31.01.2025","Fortsetzung der Druck-Ausgabe"],"disp":"Intravital microscopy Imaging host-parasite interactions in the brainCellular microbiology","type":{"bibl":"periodical","media":"Online-Ressource"},"part":{"extent":"11","volume":"21","text":"21(2019,5) Artikel-Nummer e13024, 11 Seiten","pages":"1-11","issue":"5","year":"2019"},"pubHistory":["1.1999-"]}],"origin":[{"dateIssuedKey":"2019","dateIssuedDisp":"04 March 2019"}],"id":{"doi":["10.1111/cmi.13024"],"eki":["1665671750"]},"name":{"displayForm":["Mariana De Niz, Adéla Nacer, Friedrich Frischknecht"]}} | ||
| SRT | |a NIZMARIANAINTRAVITAL0420 | ||