Clinical and histopathological features of adenomas of the ciliary pigment epithelium
Purpose Adenomas of the ciliary pigment epithelium (CPE) are rare benign tumours which have mainly to be differentiated from malignant ciliary body melanomas. Here we report on a consecutive series of patients with CPE adenomas and describe their characteristics. Methods The retrospective hospital-b...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
29 April 2016
|
| In: |
Acta ophthalmologica
Year: 2016, Jahrgang: 94, Heft: 7, Pages: e637-e643 |
| ISSN: | 1755-3768 |
| DOI: | 10.1111/aos.13029 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1111/aos.13029 Verlag, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.13029 
|
| Verfasserangaben: | Ying Chang, Wen Bin Wei, Ji Tong Shi, Jun Fang Xian, Wen Li Yang, Xiao Lin Xu, Hai Xia Bai, Bin Li and Jost B. Jonas |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1665837330 | ||
| 003 | DE-627 | ||
| 005 | 20220816153941.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 190516s2016 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1111/aos.13029 |2 doi | |
| 035 | |a (DE-627)1665837330 | ||
| 035 | |a (DE-599)KXP1665837330 | ||
| 035 | |a (OCoLC)1341224781 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Chang, Ying |e VerfasserIn |0 (DE-588)1131733223 |0 (DE-627)88640651X |0 (DE-576)48839855X |4 aut | |
| 245 | 1 | 0 | |a Clinical and histopathological features of adenomas of the ciliary pigment epithelium |c Ying Chang, Wen Bin Wei, Ji Tong Shi, Jun Fang Xian, Wen Li Yang, Xiao Lin Xu, Hai Xia Bai, Bin Li and Jost B. Jonas |
| 264 | 1 | |c 29 April 2016 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 16.05.2019 | ||
| 520 | |a Purpose Adenomas of the ciliary pigment epithelium (CPE) are rare benign tumours which have mainly to be differentiated from malignant ciliary body melanomas. Here we report on a consecutive series of patients with CPE adenomas and describe their characteristics. Methods The retrospective hospital-based case series study included all patients who were consecutively operated for CPE adenomas. Results Of the 110 patients treated for ciliary body tumours, five patients (4.5%) had a CPE adenoma. Mean age was 59.0 ± 9.9 years (range: 46-72 years). Mean tumour apical thickness was 6.6 ± 1.7 mm. Tumour colour was mostly homogenously brown to black, and the tumour surface was smooth. The tumour masses pushed the iris tissue forward without infiltrating iris or anterior chamber angle. Sonography revealed an irregular echogram with sharp lesion borders and signs of blood flow in Color Doppler flow imaging. Ultrasonographic biomicroscopy demonstrated medium-low internal reflectivity and acoustic attenuation. In magnetic resonance imaging (MRI), the tumours as compared to brain were hyperintense on T1-weighted images and hypointense on T2-weighted images. Tumour tissue consisted of cords and nests of pigment epithelium cells separated by septa of vascularized fibrous connective tissue, leading to a pseudo-glandular appearance. The melanin granules in the cytoplasm were large and mostly spherical in shape. In four patients, the tumours were hyperpigmented. Tumour cells were large with round or oval nuclei and clearly detectable nucleoli. Conclusions These clinical characteristics of CPE adenomas, such as homogenous dark brown colour, smooth surface, iris dislocation and anterior chamber angle narrowing but no iris infiltration, segmental cataract, pigment dispersion, and, as compared to brain tissue, hypointensity and, as compared to extraocular muscles or lacrimal gland, hyperintensity on T2-weighted MRI images, may be helpful for the differentiation from ciliary body malignant melanomas. | ||
| 650 | 4 | |a adenoma of the ciliary pigment epithelium | |
| 650 | 4 | |a ciliary body tumour | |
| 650 | 4 | |a ciliary malignant melanoma | |
| 650 | 4 | |a ocular pathology | |
| 700 | 1 | |a Jonas, Jost B. |d 1958- |e VerfasserIn |0 (DE-588)1028286732 |0 (DE-627)730536823 |0 (DE-576)37578537X |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Acta ophthalmologica |d Oxford : Blackwell, 2008 |g 94(2016), 7, Seite e637-e643 |h Online-Ressource |w (DE-627)585797218 |w (DE-600)2466981-7 |w (DE-576)290238277 |x 1755-3768 |7 nnas |a Clinical and histopathological features of adenomas of the ciliary pigment epithelium |
| 773 | 1 | 8 | |g volume:94 |g year:2016 |g number:7 |g pages:e637-e643 |g extent:7 |a Clinical and histopathological features of adenomas of the ciliary pigment epithelium |
| 856 | 4 | 0 | |u https://doi.org/10.1111/aos.13029 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.13029 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20190516 | ||
| 993 | |a Article | ||
| 994 | |a 2016 | ||
| 998 | |g 1028286732 |a Jonas, Jost B. |m 1028286732:Jonas, Jost B. |d 60000 |e 60000PJ1028286732 |k 0/60000/ |p 9 |y j | ||
| 999 | |a KXP-PPN1665837330 |e 3476613070 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"language":["eng"],"person":[{"given":"Ying","role":"aut","family":"Chang","display":"Chang, Ying"},{"role":"aut","given":"Jost B.","display":"Jonas, Jost B.","family":"Jonas"}],"id":{"doi":["10.1111/aos.13029"],"eki":["1665837330"]},"name":{"displayForm":["Ying Chang, Wen Bin Wei, Ji Tong Shi, Jun Fang Xian, Wen Li Yang, Xiao Lin Xu, Hai Xia Bai, Bin Li and Jost B. Jonas"]},"physDesc":[{"extent":"7 S."}],"relHost":[{"part":{"text":"94(2016), 7, Seite e637-e643","issue":"7","year":"2016","pages":"e637-e643","volume":"94","extent":"7"},"language":["eng"],"corporate":[{"role":"isb","display":"European Association for Vision and Eye Research"}],"id":{"zdb":["2466981-7"],"issn":["1755-3768"],"doi":["10.1111/(ISSN)1755-3768"],"eki":["585797218"]},"recId":"585797218","name":{"displayForm":["European Association for Vision and Eye Research"]},"physDesc":[{"extent":"Online-Ressource"}],"disp":"Clinical and histopathological features of adenomas of the ciliary pigment epitheliumActa ophthalmologica","type":{"bibl":"periodical","media":"Online-Ressource"},"origin":[{"publisherPlace":"Oxford","dateIssuedKey":"2008","publisher":"Blackwell","dateIssuedDisp":"2008-"}],"note":["Gesehen am 25.03.22"],"pubHistory":["86.2008 -"],"title":[{"title_sort":"Acta ophthalmologica","subtitle":"the official journal of the Nordic Ophthalmological Societies","title":"Acta ophthalmologica"}]}],"recId":"1665837330","type":{"bibl":"article-journal","media":"Online-Ressource"},"note":["Gesehen am 16.05.2019"],"origin":[{"dateIssuedDisp":"29 April 2016","dateIssuedKey":"2016"}],"title":[{"title_sort":"Clinical and histopathological features of adenomas of the ciliary pigment epithelium","title":"Clinical and histopathological features of adenomas of the ciliary pigment epithelium"}]} | ||
| SRT | |a CHANGYINGJCLINICALAN2920 | ||