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Patient-specific online dose verification based on transmission detector measurements

Background and purpose - Since IMRT-techniques lead to an increasingly complicated environment, a patient specific IMRT-plan verification is recommended. Furthermore, verifications during patient irradiation and 3D dose reconstruction have the potential to improve treatment delivery, accuracy and sa...

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Main Authors: Thölking, Johannes (Author) , Fleckenstein, Jens (Author) , Sekar, Yuvaraj (Author) , Lohr, Frank (Author) , Wenz, Frederik (Author) , Wertz, Hansjörg (Author)
Format: Article (Journal)
Language:English
Published: 16 April 2016
In: Radiotherapy and oncology
Year: 2016, Volume: 119, Issue: 2, Pages: 351-356
ISSN:1879-0887
DOI:10.1016/j.radonc.2016.04.003
Online Access:Verlag, Volltext: https://doi.org/10.1016/j.radonc.2016.04.003
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0167814016310374
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Author Notes:Johannes Thoelking, Jens Fleckenstein, Yuvaraj Sekar, Ramesh Boggula, Frank Lohr, Frederik Wenz, Hansjoerg Wertz

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520 |a Background and purpose - Since IMRT-techniques lead to an increasingly complicated environment, a patient specific IMRT-plan verification is recommended. Furthermore, verifications during patient irradiation and 3D dose reconstruction have the potential to improve treatment delivery, accuracy and safety. This study provides a detailed investigation of the new transmission detector (DTD) Dolphin (IBA Dosimetry, Germany) for online dosimetry. - Materials and methods - The clinical performance of the DTD was tested by dosimetric plan verification in 2D and 3D for 18 IMRT-sequences. In 2D, DTD measurements were compared to a pre-treatment verification method and a treatment planning system by gamma index and dose difference evaluations. In 3D, dose-volume-histogram (DVH) indices and gamma analysis were evaluated. Furthermore, the error detection ability was tested with leaf position uncertainties and deviations in the linear accelerator (LINAC) output. - Results - The DTD measurements were in excellent agreement to reference measurements in both 2D (γ3%,3mm=(99.7±0.6)% <1, ΔD±5%=(99.5±0.5)%) and 3D. Only a small dose underestimation (<2%) within the target volume was observed when analyzing DVH-indices. Positional errors of the leaf banks larger than 1mm and errors in LINAC output larger than 2% were identified with the DTD. - Conclusions - The DTD measures the delivered dose with sufficient accuracy and is therefore suitable for clinical routine. 
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