Filtration markers and determination methods for the assessment of kidney function

Estimation of renal function is crucial for a number of clinical situations. Endogenous markers such as creatinine, as well as several exogenous agents including inulin, 99mTc-DTPA and iothalamate are used for evaluation of kidney function. At present, new generation filtration markers and determina...

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Hauptverfasser: Huang, Jiaguo (VerfasserIn) , Gretz, Norbert (VerfasserIn) , Weinfurter, Stefanie (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 5 November 2016
In: European journal of pharmacology
Year: 2016, Jahrgang: 790, Pages: 92-98
ISSN:1879-0712
DOI:10.1016/j.ejphar.2016.06.060
Online-Zugang:Verlag, Volltext: https://doi.org/10.1016/j.ejphar.2016.06.060
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0014299916304290
Volltext
Verfasserangaben:Jiaguo Huang, Norbert Gretz, Stefanie Weinfurter

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520 |a Estimation of renal function is crucial for a number of clinical situations. Endogenous markers such as creatinine, as well as several exogenous agents including inulin, 99mTc-DTPA and iothalamate are used for evaluation of kidney function. At present, new generation filtration markers and determination methods based on organic fluorescent dyes and fluorescent detection technique are developed. This review gives an overview of filtration markers and clearance methods for the assessment of kidney function. New filtration markers and transcutaneous measurement of renal function are described. Problems and issues relating to the reabsorption or secretion of each of markers and the applicability of methods are also discussed. 
650 4 |a Clearance methods 
650 4 |a Filtration markers 
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650 4 |a Glomerular filtration rate 
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