Association analyses identify 31 new risk loci for colorectal cancer susceptibility
In colorectal cancer (CRC), finding loci associated with risk may give insight into disease aetiology. Here, the authors report a genome-wide association analysis in Europeans of 34,627 CRC cases and 71,379 controls, and find 31 new risk loci and 17 new risk SNPs at previously reported loci.
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2019
|
| In: |
Nature Communications
Year: 2019, Volume: 10 |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-019-09775-w |
| Online Access: | Verlag, Volltext: https://doi.org/10.1038/s41467-019-09775-w Verlag, Volltext: https://www.nature.com/articles/s41467-019-09775-w 
|
| Author Notes: | Philip J. Law, Maria Timofeeva, Ceres Fernandez-Rozadilla, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner et al. |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1666524697 | ||
| 003 | DE-627 | ||
| 005 | 20230426220608.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 190529s2019 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1038/s41467-019-09775-w |2 doi | |
| 035 | |a (DE-627)1666524697 | ||
| 035 | |a (DE-599)KXP1666524697 | ||
| 035 | |a (OCoLC)1341225863 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Law, Philip J. |e VerfasserIn |0 (DE-588)1155603613 |0 (DE-627)1017877912 |0 (DE-576)501770127 |4 aut | |
| 245 | 1 | 0 | |a Association analyses identify 31 new risk loci for colorectal cancer susceptibility |c Philip J. Law, Maria Timofeeva, Ceres Fernandez-Rozadilla, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner et al. |
| 246 | 3 | 3 | |a thirty-one |
| 264 | 1 | |c 2019 | |
| 300 | |a 15 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 29.05.2019 | ||
| 520 | |a In colorectal cancer (CRC), finding loci associated with risk may give insight into disease aetiology. Here, the authors report a genome-wide association analysis in Europeans of 34,627 CRC cases and 71,379 controls, and find 31 new risk loci and 17 new risk SNPs at previously reported loci. | ||
| 700 | 1 | |a Chang-Claude, Jenny |e VerfasserIn |0 (DE-588)1049304993 |0 (DE-627)781626188 |0 (DE-576)168344475 |4 aut | |
| 700 | 1 | |a Hoffmeister, Michael |d 1973- |e VerfasserIn |0 (DE-588)134103726 |0 (DE-627)560880820 |0 (DE-576)277089565 |4 aut | |
| 700 | 1 | |a Brenner, Hermann |e VerfasserIn |0 (DE-588)1020516445 |0 (DE-627)691247005 |0 (DE-576)360642136 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Nature Communications |d [London] : Springer Nature, 2010 |g 10(2019) Artikel-Nummer 2154, 15 Seiten |h Online-Ressource |w (DE-627)626457688 |w (DE-600)2553671-0 |w (DE-576)331555905 |x 2041-1723 |7 nnas |a Association analyses identify 31 new risk loci for colorectal cancer susceptibility |
| 773 | 1 | 8 | |g volume:10 |g year:2019 |g extent:15 |a Association analyses identify 31 new risk loci for colorectal cancer susceptibility |
| 856 | 4 | 0 | |u https://doi.org/10.1038/s41467-019-09775-w |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://www.nature.com/articles/s41467-019-09775-w |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20190529 | ||
| 993 | |a Article | ||
| 994 | |a 2019 | ||
| 998 | |g 1020516445 |a Brenner, Hermann |m 1020516445:Brenner, Hermann |d 850000 |d 851600 |d 50000 |e 850000PB1020516445 |e 851600PB1020516445 |e 50000PB1020516445 |k 0/850000/ |k 1/850000/851600/ |k 0/50000/ |p 88 | ||
| 998 | |g 134103726 |a Hoffmeister, Michael |m 134103726:Hoffmeister, Michael |d 50000 |e 50000PH134103726 |k 0/50000/ |p 87 | ||
| 998 | |g 1049304993 |a Chang-Claude, Jenny |m 1049304993:Chang-Claude, Jenny |d 50000 |e 50000PC1049304993 |k 0/50000/ |p 86 | ||
| 999 | |a KXP-PPN1666524697 |e 3480177255 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"type":{"media":"Online-Ressource","bibl":"article-journal"},"id":{"doi":["10.1038/s41467-019-09775-w"],"eki":["1666524697"]},"titleAlt":[{"title":"thirty-one"}],"recId":"1666524697","origin":[{"dateIssuedKey":"2019","dateIssuedDisp":"2019"}],"language":["eng"],"person":[{"given":"Philip J.","family":"Law","role":"aut","display":"Law, Philip J."},{"given":"Jenny","family":"Chang-Claude","role":"aut","display":"Chang-Claude, Jenny"},{"role":"aut","display":"Hoffmeister, Michael","given":"Michael","family":"Hoffmeister"},{"family":"Brenner","given":"Hermann","display":"Brenner, Hermann","role":"aut"}],"relHost":[{"language":["eng"],"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title_sort":"Nature Communications","title":"Nature Communications"}],"disp":"Association analyses identify 31 new risk loci for colorectal cancer susceptibilityNature Communications","note":["Gesehen am 13.06.24"],"type":{"bibl":"periodical","media":"Online-Ressource"},"id":{"eki":["626457688"],"zdb":["2553671-0"],"issn":["2041-1723"]},"part":{"extent":"15","year":"2019","volume":"10","text":"10(2019) Artikel-Nummer 2154, 15 Seiten"},"pubHistory":["2010-"],"recId":"626457688","origin":[{"publisherPlace":"[London] ; [London]","dateIssuedDisp":"[2010]-","publisher":"Springer Nature ; Nature Publishing Group UK"}]}],"title":[{"title":"Association analyses identify 31 new risk loci for colorectal cancer susceptibility","title_sort":"Association analyses identify 31 new risk loci for colorectal cancer susceptibility"}],"physDesc":[{"extent":"15 S."}],"note":["Gesehen am 29.05.2019"],"name":{"displayForm":["Philip J. Law, Maria Timofeeva, Ceres Fernandez-Rozadilla, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner et al."]}} | ||
| SRT | |a LAWPHILIPJASSOCIATIO2019 | ||