Association analyses identify 31 new risk loci for colorectal cancer susceptibility

In colorectal cancer (CRC), finding loci associated with risk may give insight into disease aetiology. Here, the authors report a genome-wide association analysis in Europeans of 34,627 CRC cases and 71,379 controls, and find 31 new risk loci and 17 new risk SNPs at previously reported loci.

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Bibliographische Detailangaben
Hauptverfasser: Law, Philip J. (VerfasserIn) , Chang-Claude, Jenny (VerfasserIn) , Hoffmeister, Michael (VerfasserIn) , Brenner, Hermann (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2019
In: Nature Communications
Year: 2019, Jahrgang: 10
ISSN:2041-1723
DOI:10.1038/s41467-019-09775-w
Online-Zugang:Verlag, Volltext: https://doi.org/10.1038/s41467-019-09775-w
Verlag, Volltext: https://www.nature.com/articles/s41467-019-09775-w
Volltext
Verfasserangaben:Philip J. Law, Maria Timofeeva, Ceres Fernandez-Rozadilla, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner et al.
Beschreibung
Zusammenfassung:In colorectal cancer (CRC), finding loci associated with risk may give insight into disease aetiology. Here, the authors report a genome-wide association analysis in Europeans of 34,627 CRC cases and 71,379 controls, and find 31 new risk loci and 17 new risk SNPs at previously reported loci.
Beschreibung:Gesehen am 29.05.2019
Beschreibung:Online Resource
ISSN:2041-1723
DOI:10.1038/s41467-019-09775-w