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Recent advances in the structural and mechanistic aspects of Hsp70 molecular chaperones

Hsp70 chaperones are central hubs of the protein quality control network and collaborate with co-chaperones having a J-domain (an ∼70-residue-long helical hairpin with a flexible loop and a conserved His-Pro-Asp motif required for ATP hydrolysis by Hsp70s) and also with nucleotide exchange factors t...

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Bibliographic Details
Main Authors: Mayer, Matthias P. (Author) , Gierasch, Lila M. (Author)
Format: Article (Journal)
Language:English
Published: 2019
In: The journal of biological chemistry
Year: 2018, Volume: 294, Issue: 6, Pages: 2085-2097
ISSN:1083-351X
DOI:10.1074/jbc.REV118.002810
Online Access:Verlag, Volltext: https://doi.org/10.1074/jbc.REV118.002810
Verlag, Volltext: http://www.jbc.org/content/294/6/2085
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Author Notes:Matthias P. Mayer and Lila M. Gierasch

MARC

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