WEADE: a workflow for enrichment analysis and data exploration
Data analysis based on enrichment of Gene Ontology terms has become an important step in exploring large gene or protein expression datasets and several stand-alone or web tools exist for that purpose. However, a comprehensive and consistent analysis downstream of the enrichment calculation is missi...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
September 28, 2018
|
| In: |
PLOS ONE
Year: 2018, Volume: 13, Issue: 9 |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0204016 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1371/journal.pone.0204016 Verlag, Volltext: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204016 |
| Author Notes: | Nils Trost, Eugen Rempel, Olga Ermakova, Srividya Tamirisa, Letiția Pârcălăbescu, Michael Boutros, Jan U. Lohmann, Ingrid Lohmann |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1666682241 | ||
| 003 | DE-627 | ||
| 005 | 20220816164905.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 190604s2018 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1371/journal.pone.0204016 |2 doi | |
| 035 | |a (DE-627)1666682241 | ||
| 035 | |a (DE-599)KXP1666682241 | ||
| 035 | |a (OCoLC)1341225873 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Trost, Nils |d 1993- |e VerfasserIn |0 (DE-588)1185523782 |0 (DE-627)1664868070 |4 aut | |
| 245 | 1 | 0 | |a WEADE |b a workflow for enrichment analysis and data exploration |c Nils Trost, Eugen Rempel, Olga Ermakova, Srividya Tamirisa, Letiția Pârcălăbescu, Michael Boutros, Jan U. Lohmann, Ingrid Lohmann |
| 264 | 1 | |c September 28, 2018 | |
| 300 | |a 10 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 04.06.2019 | ||
| 520 | |a Data analysis based on enrichment of Gene Ontology terms has become an important step in exploring large gene or protein expression datasets and several stand-alone or web tools exist for that purpose. However, a comprehensive and consistent analysis downstream of the enrichment calculation is missing so far. With WEADE we present a free web application that offers an integrated workflow for the exploration of genomic data combining enrichment analysis with a versatile set of tools to directly compare and intersect experiments or candidate gene lists of any size or origin including cross-species data. Lastly, WEADE supports the graphical representation of output data in the form of functional interaction networks based on prior knowledge, allowing users to go from plain expression data to functionally relevant candidate sub-lists in an interactive and consistent manner. | ||
| 650 | 4 | |a Gene ontologies | |
| 650 | 4 | |a Genetic networks | |
| 650 | 4 | |a Genome analysis | |
| 650 | 4 | |a Interaction networks | |
| 650 | 4 | |a Ontologies | |
| 650 | 4 | |a Species diversity | |
| 650 | 4 | |a User interfaces | |
| 650 | 4 | |a Web-based applications | |
| 700 | 1 | |a Rempel, Eugen |d 1979- |e VerfasserIn |0 (DE-588)1116610396 |0 (DE-627)870570269 |0 (DE-576)478523572 |4 aut | |
| 700 | 1 | |a Ermakova, Olga |e VerfasserIn |0 (DE-588)1161625399 |0 (DE-627)1024914194 |0 (DE-576)506773779 |4 aut | |
| 700 | 1 | |a Tamirisa, Srividya |e VerfasserIn |0 (DE-588)1185522573 |0 (DE-627)1664866221 |4 aut | |
| 700 | 1 | |a Pârcălăbescu, Letiția |d 1994- |e VerfasserIn |0 (DE-588)118777586X |0 (DE-627)1666681547 |4 aut | |
| 700 | 1 | |a Lohmann, Jan U. |d 1971- |e VerfasserIn |0 (DE-588)121572315 |0 (DE-627)70554642X |0 (DE-576)292778627 |4 aut | |
| 700 | 1 | |a Lohmann, Ingrid |e VerfasserIn |0 (DE-588)1047761831 |0 (DE-627)779177215 |0 (DE-576)401571688 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t PLOS ONE |d San Francisco, California, US : PLOS, 2006 |g 13(2018,9) Artikel-Nummer e0204016, 10 Seiten |h Online-Ressource |w (DE-627)523574592 |w (DE-600)2267670-3 |w (DE-576)281331979 |x 1932-6203 |7 nnas |a WEADE a workflow for enrichment analysis and data exploration |
| 773 | 1 | 8 | |g volume:13 |g year:2018 |g number:9 |g extent:10 |a WEADE a workflow for enrichment analysis and data exploration |
| 856 | 4 | 0 | |u https://doi.org/10.1371/journal.pone.0204016 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204016 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20190604 | ||
| 993 | |a Article | ||
| 994 | |a 2018 | ||
| 998 | |g 1047761831 |a Lohmann, Ingrid |m 1047761831:Lohmann, Ingrid |d 700000 |d 721000 |e 700000PL1047761831 |e 721000PL1047761831 |k 0/700000/ |k 1/700000/721000/ |p 8 |y j | ||
| 998 | |g 121572315 |a Lohmann, Jan U. |m 121572315:Lohmann, Jan U. |d 700000 |d 721000 |d 700000 |d 718000 |e 700000PL121572315 |e 721000PL121572315 |e 700000PL121572315 |e 718000PL121572315 |k 0/700000/ |k 1/700000/721000/ |k 0/700000/ |k 1/700000/718000/ |p 7 | ||
| 998 | |g 118777586X |a Pârcălăbescu, Letiția |m 118777586X:Pârcălăbescu, Letiția |d 700000 |d 721000 |d 90000 |d 90500 |e 700000PP118777586X |e 721000PP118777586X |e 90000PP118777586X |e 90500PP118777586X |k 0/700000/ |k 1/700000/721000/ |k 0/90000/ |k 1/90000/90500/ |p 5 | ||
| 998 | |g 1185522573 |a Tamirisa, Srividya |m 1185522573:Tamirisa, Srividya |d 700000 |d 721000 |e 700000PT1185522573 |e 721000PT1185522573 |k 0/700000/ |k 1/700000/721000/ |p 4 | ||
| 998 | |g 1161625399 |a Ermakova, Olga |m 1161625399:Ermakova, Olga |d 700000 |d 721000 |e 700000PE1161625399 |e 721000PE1161625399 |k 0/700000/ |k 1/700000/721000/ |p 3 | ||
| 998 | |g 1116610396 |a Rempel, Eugen |m 1116610396:Rempel, Eugen |d 910000 |d 912000 |e 910000PR1116610396 |e 912000PR1116610396 |k 0/910000/ |k 1/910000/912000/ |p 2 | ||
| 998 | |g 1185523782 |a Trost, Nils |m 1185523782:Trost, Nils |d 700000 |d 721000 |e 700000PT1185523782 |e 721000PT1185523782 |k 0/700000/ |k 1/700000/721000/ |p 1 |x j | ||
| 999 | |a KXP-PPN1666682241 |e 348092994X | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1666682241","id":{"eki":["1666682241"],"doi":["10.1371/journal.pone.0204016"]},"name":{"displayForm":["Nils Trost, Eugen Rempel, Olga Ermakova, Srividya Tamirisa, Letiția Pârcălăbescu, Michael Boutros, Jan U. Lohmann, Ingrid Lohmann"]},"person":[{"given":"Nils","family":"Trost","display":"Trost, Nils","role":"aut","roleDisplay":"VerfasserIn"},{"role":"aut","display":"Rempel, Eugen","roleDisplay":"VerfasserIn","family":"Rempel","given":"Eugen"},{"display":"Ermakova, Olga","role":"aut","roleDisplay":"VerfasserIn","family":"Ermakova","given":"Olga"},{"roleDisplay":"VerfasserIn","role":"aut","display":"Tamirisa, Srividya","given":"Srividya","family":"Tamirisa"},{"role":"aut","display":"Pârcălăbescu, Letiția","roleDisplay":"VerfasserIn","family":"Pârcălăbescu","given":"Letiția"},{"role":"aut","display":"Lohmann, Jan U.","roleDisplay":"VerfasserIn","family":"Lohmann","given":"Jan U."},{"role":"aut","display":"Lohmann, Ingrid","roleDisplay":"VerfasserIn","family":"Lohmann","given":"Ingrid"}],"note":["Gesehen am 04.06.2019"],"physDesc":[{"extent":"10 S."}],"language":["eng"],"relHost":[{"name":{"displayForm":["Public Library of Science"]},"pubHistory":["1.2006 -"],"note":["Schreibweise des Titels bis 2012: PLoS ONE","Gesehen am 20.03.19"],"physDesc":[{"extent":"Online-Ressource"}],"recId":"523574592","id":{"eki":["523574592"],"zdb":["2267670-3"],"issn":["1932-6203"]},"corporate":[{"display":"Public Library of Science","role":"isb","roleDisplay":"Herausgebendes Organ"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"language":["eng"],"part":{"issue":"9","year":"2018","volume":"13","extent":"10","text":"13(2018,9) Artikel-Nummer e0204016, 10 Seiten"},"disp":"WEADE a workflow for enrichment analysis and data explorationPLOS ONE","origin":[{"dateIssuedDisp":"2006-","publisherPlace":"San Francisco, California, US ; Lawrence, Kan.","dateIssuedKey":"2006","publisher":"PLOS ; PLoS"}],"title":[{"title_sort":"PLOS ONE","title":"PLOS ONE"}]}],"origin":[{"dateIssuedKey":"2018","dateIssuedDisp":"September 28, 2018"}],"title":[{"subtitle":"a workflow for enrichment analysis and data exploration","title_sort":"WEADE","title":"WEADE"}],"type":{"bibl":"article-journal","media":"Online-Ressource"}} | ||
| SRT | |a TROSTNILSRWEADE2820 | ||