Polygenic risk scores for prediction of breast cancer and breast cancer subtypes
Stratification of women according to their risk of breast cancer based on polygenic risk scores (PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, optimized for prediction of estrogen receptor (ER)-specific disease, from the largest available genome-wide associati...
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| Hauptverfasser: | , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2019
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| In: |
American journal of human genetics
Year: 2019, Jahrgang: 104, Heft: 1, Pages: 21-34 |
| ISSN: | 0002-9297 |
| DOI: | 10.1016/j.ajhg.2018.11.002 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1016/j.ajhg.2018.11.002 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0002929718304051 |
| Verfasserangaben: | Nasim Mavaddat, Volker Arndt, Hermann Brenner, Barbara Burwinkel, Asta Försti, Rudolf Kaaks, Andreas Schneeweiss, Christof Sohn, Yan Zhang [und weitere] |
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