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Phase II clinical trial of pazopanib in patients with acute myeloid leukemia (AML), relapsed or refractory or at initial diagnosis without an intensive treatment option (PazoAML)

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We evaluated pazopanib (800 mg orally QD) in patients not eligible for intensive treatment with relapsed/refractory AML or at initial diagnosis. Patients receiving pazopanib for > 14 days were analyzed for safety, tolerability, and efficacy. Co-primary endpoints were cumulative response rate and...

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Main Authors: Keßler, Torsten (Author) , Müller-Tidow, Carsten (Author)
Format: Article (Journal)
Language:English
Published: 21 March 2019
In: Annals of hematology
Year: 2019, Volume: 98, Issue: 6, Pages: 1393-1401
ISSN:1432-0584
DOI:10.1007/s00277-019-03651-9
Online Access:Verlag, Pay-per-use, Volltext: https://doi.org/10.1007/s00277-019-03651-9
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Author Notes:Torsten Kessler, Steffen Koschmieder, Christoph Schliemann, Martina Crysandt, Jan-Henrik Mikesch, Saskia von Stillfried, Matthias Stelljes, Michele Pohlen, Georg Lenz, Anna Kirsch, Kerstin Vehring, Eva Wardelmann, Wolfgang Hartmann, Eike Bormann, Joachim Gerss, Tim H. Brümmendorf, Carsten Müller-Tidow, Wolfgang E. Berdel
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Author correction: Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia by Göllner, Stefanie (Author) , Oellerich, Thomas (Author) , Agrawal-Singh, Shuchi (Author) , Schenk, Tino (Author) , Klein, Hans-Ulrich (Author) , Rohde, Christian (Author) , Pabst, Caroline (Author) , Sauer, Tim (Author) , Lerdrup, Mads (Author) , Tavor, Sigal (Author) , Stölzel, Friedrich (Author) , Herold, Sylvia (Author) , Ehninger, Gerhard (Author) , Köhler, Gabriele (Author) , Pan, Kuan-Ting (Author) , Urlaub, Henning (Author) , Serve, Hubert (Author) , Dugas, Martin (Author) , Spiekermann, Karsten (Author) , Vick, Binje (Author) , Jeremias, Irmela (Author) , Berdel, Wolfgang E. (Author) , Hansen, Klaus (Author) , Zelent, Arthur (Author) , Wickenhauser, Claudia (Author) , Müller, Lutz P. (Author) , Thiede, Christian (Author) , Müller-Tidow, Carsten (Author) ,


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