Meningiomas: overview and new directions in therapy
The majority of meningiomas, the most common primary brain tumor, are considered to be benign, and characteristic magnetic resonance imaging features allow a preliminary diagnosis. Meningiomas can be classified in the World Health Organization system as grade I, II, or III, depending on various hist...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2018
|
| In: |
Seminars in neurology
Year: 2018, Jahrgang: 38, Heft: 1, Pages: 112-120 |
| ISSN: | 1098-9021 |
| DOI: | 10.1055/s-0038-1636502 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1055/s-0038-1636502
|
| Verfasserangaben: | Nancy Wang, Matthias Osswald |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 166763724X | ||
| 003 | DE-627 | ||
| 005 | 20220816172936.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 190619s2018 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1055/s-0038-1636502 |2 doi | |
| 035 | |a (DE-627)166763724X | ||
| 035 | |a (DE-599)KXP166763724X | ||
| 035 | |a (OCoLC)1341228974 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Wang, Nancy |e VerfasserIn |0 (DE-588)1188730320 |0 (DE-627)1667637908 |4 aut | |
| 245 | 1 | 0 | |a Meningiomas |b overview and new directions in therapy |c Nancy Wang, Matthias Osswald |
| 264 | 1 | |c 2018 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 19.06.2019 | ||
| 520 | |a The majority of meningiomas, the most common primary brain tumor, are considered to be benign, and characteristic magnetic resonance imaging features allow a preliminary diagnosis. Meningiomas can be classified in the World Health Organization system as grade I, II, or III, depending on various histological features. In many cases, observation is the preferred management option, although this means the absence of a histological diagnosis. If necessary, standard therapy consists of surgery with or without adjuvant radiation, depending on the tumor grade and the degree of resection. To date, systemic therapies are not included in the standard of care. The level of evidence for treatment recommendations is low, and effective treatment regimens, especially for surgery-refractory and radiation-refractory meningiomas, are still very limited. Recent studies have broadened our knowledge of the genetics and pathogenesis of meningiomas and will lead to new therapeutic options. This review summarizes the epidemiology, pathogenesis and genetics, classification, and diagnosis of meningiomas, as well as management principles, including promising new avenues of therapy. | ||
| 650 | 4 | |a Humans | |
| 650 | 4 | |a Meningeal Neoplasms | |
| 650 | 4 | |a Meningioma | |
| 700 | 1 | |a Osswald, Matthias |d 1982- |e VerfasserIn |0 (DE-588)139015620 |0 (DE-627)703181645 |0 (DE-576)309419069 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Seminars in neurology |d New York, NY : Thieme Medical Publ., 1981 |g 38(2018), 1, Seite 112-120 |h Online-Ressource |w (DE-627)342892835 |w (DE-600)2072477-9 |w (DE-576)279447876 |x 1098-9021 |7 nnas |a Meningiomas overview and new directions in therapy |
| 773 | 1 | 8 | |g volume:38 |g year:2018 |g number:1 |g pages:112-120 |g extent:9 |a Meningiomas overview and new directions in therapy |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1055/s-0038-1636502 |x Verlag |x Resolving-System |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20190619 | ||
| 993 | |a Article | ||
| 994 | |a 2018 | ||
| 998 | |g 139015620 |a Osswald, Matthias |m 139015620:Osswald, Matthias |d 910000 |d 911100 |e 910000PO139015620 |e 911100PO139015620 |k 0/910000/ |k 1/910000/911100/ |p 2 |y j | ||
| 999 | |a KXP-PPN166763724X |e 3488336158 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"display":"Wang, Nancy","roleDisplay":"VerfasserIn","role":"aut","family":"Wang","given":"Nancy"},{"roleDisplay":"VerfasserIn","display":"Osswald, Matthias","role":"aut","family":"Osswald","given":"Matthias"}],"title":[{"title_sort":"Meningiomas","subtitle":"overview and new directions in therapy","title":"Meningiomas"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"note":["Gesehen am 19.06.2019"],"language":["eng"],"recId":"166763724X","name":{"displayForm":["Nancy Wang, Matthias Osswald"]},"origin":[{"dateIssuedDisp":"2018","dateIssuedKey":"2018"}],"id":{"doi":["10.1055/s-0038-1636502"],"eki":["166763724X"]},"physDesc":[{"extent":"9 S."}],"relHost":[{"note":["Gesehen am 28.06.2017"],"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Meningiomas overview and new directions in therapySeminars in neurology","language":["eng"],"recId":"342892835","pubHistory":["1.1981 -"],"part":{"pages":"112-120","issue":"1","year":"2018","extent":"9","volume":"38","text":"38(2018), 1, Seite 112-120"},"title":[{"title_sort":"Seminars in neurology","title":"Seminars in neurology"}],"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"publisherPlace":"New York, NY ; Stuttgart","dateIssuedKey":"1981","publisher":"Thieme Medical Publ.","dateIssuedDisp":"1981-"}],"id":{"zdb":["2072477-9"],"doi":["10.1055/s-00000071"],"eki":["342892835"],"issn":["1098-9021"]}}]} | ||
| SRT | |a WANGNANCYOMENINGIOMA2018 | ||