Gastroesophageal reflux disease in idiopathic pulmonary fibrosis: uncertainties and controversies
The mechanisms of idiopathic pulmonary fibrosis (IPF), a rare, devastating disease with a median survival of 3-5 years, are not fully understood. Gastroesophageal reflux disease (GERD) is a frequent comorbidity encountered in IPF. Hypothetically, GERD-associated microaspiration may lead to persisten...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2018
|
| In: |
Respiration
Year: 2018, Volume: 96, Issue: 6, Pages: 571-587 |
| ISSN: | 1423-0356 |
| DOI: | 10.1159/000492336 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1159/000492336
|
| Author Notes: | Zheng Wang, Francesco Bonella, Wenting Li, Eda B. Boerner, Qiongya Guo, Xianglong Kong, Xiaoju Zhang, Ulrich Costabel, Michael Kreuter |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1667808117 | ||
| 003 | DE-627 | ||
| 005 | 20230427035409.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 190624s2018 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1159/000492336 |2 doi | |
| 035 | |a (DE-627)1667808117 | ||
| 035 | |a (DE-599)KXP1667808117 | ||
| 035 | |a (OCoLC)1341229186 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Wang, Zheng |e VerfasserIn |0 (DE-588)1189079941 |0 (DE-627)1667810979 |4 aut | |
| 245 | 1 | 0 | |a Gastroesophageal reflux disease in idiopathic pulmonary fibrosis |b uncertainties and controversies |c Zheng Wang, Francesco Bonella, Wenting Li, Eda B. Boerner, Qiongya Guo, Xianglong Kong, Xiaoju Zhang, Ulrich Costabel, Michael Kreuter |
| 264 | 1 | |c 2018 | |
| 300 | |a 17 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 24.06.2019 | ||
| 520 | |a The mechanisms of idiopathic pulmonary fibrosis (IPF), a rare, devastating disease with a median survival of 3-5 years, are not fully understood. Gastroesophageal reflux disease (GERD) is a frequent comorbidity encountered in IPF. Hypothetically, GERD-associated microaspiration may lead to persistent inflammation impairing lung infrastructure, thereby possibly accelerating the progression of IPF. IPF may increase intrathoracic pressure, which can aggravate GERD and vice versa. On the basis of the possible beneficial effects of antireflux or antacid therapy on lung function, acute exacerbation, and survival, the recent international IPF guideline recommends antacid therapies for patients with IPF, regardless of symptomatic GERD. However, due to newer conflicting data, several national guidelines do not support this recommendation. Elucidation of these questions by further clinical and bench-to-bedside research may provide us with rational clinical diagnostic and therapeutic approaches concerning GERD in IPF. The present review aims to discuss the latest data on the controversial association of IPF and GERD. | ||
| 650 | 4 | |a Acute exacerbation | |
| 650 | 4 | |a Antacid therapy | |
| 650 | 4 | |a Gastroesophageal reflux | |
| 650 | 4 | |a Idiopathic pulmonary fibrosis | |
| 650 | 4 | |a Microaspiration | |
| 650 | 4 | |a Proton pump inhibitor | |
| 700 | 1 | |a Kreuter, Michael |d 1972- |e VerfasserIn |0 (DE-588)122645995 |0 (DE-627)082066795 |0 (DE-576)293362742 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Respiration |d Basel : Karger, 1968 |g 96(2018), 6, Seite 571-587 |h Online-Ressource |w (DE-627)26551035X |w (DE-600)1464419-8 |w (DE-576)112815111 |x 1423-0356 |7 nnas |a Gastroesophageal reflux disease in idiopathic pulmonary fibrosis uncertainties and controversies |
| 773 | 1 | 8 | |g volume:96 |g year:2018 |g number:6 |g pages:571-587 |g extent:17 |a Gastroesophageal reflux disease in idiopathic pulmonary fibrosis uncertainties and controversies |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1159/000492336 |x Verlag |x Resolving-System |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20190624 | ||
| 993 | |a Article | ||
| 994 | |a 2018 | ||
| 998 | |g 122645995 |a Kreuter, Michael |m 122645995:Kreuter, Michael |d 910000 |d 950000 |d 950900 |d 50000 |e 910000PK122645995 |e 950000PK122645995 |e 950900PK122645995 |e 50000PK122645995 |k 0/910000/ |k 1/910000/950000/ |k 2/910000/950000/950900/ |k 0/50000/ |p 9 |y j | ||
| 999 | |a KXP-PPN1667808117 |e 3489363418 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"display":"Wang, Zheng","roleDisplay":"VerfasserIn","given":"Zheng","family":"Wang","role":"aut"},{"roleDisplay":"VerfasserIn","given":"Michael","display":"Kreuter, Michael","family":"Kreuter","role":"aut"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"title":[{"title":"Gastroesophageal reflux disease in idiopathic pulmonary fibrosis","subtitle":"uncertainties and controversies","title_sort":"Gastroesophageal reflux disease in idiopathic pulmonary fibrosis"}],"recId":"1667808117","id":{"eki":["1667808117"],"doi":["10.1159/000492336"]},"name":{"displayForm":["Zheng Wang, Francesco Bonella, Wenting Li, Eda B. Boerner, Qiongya Guo, Xianglong Kong, Xiaoju Zhang, Ulrich Costabel, Michael Kreuter"]},"note":["Gesehen am 24.06.2019"],"relHost":[{"disp":"Gastroesophageal reflux disease in idiopathic pulmonary fibrosis uncertainties and controversiesRespiration","language":["eng"],"title":[{"title_sort":"Respiration","subtitle":"international journal of thoracic medicine","title":"Respiration"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"note":["Gesehen am 03.07.2024"],"part":{"text":"96(2018), 6, Seite 571-587","extent":"17","volume":"96","issue":"6","pages":"571-587","year":"2018"},"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"dateIssuedKey":"1968","publisherPlace":"Basel","dateIssuedDisp":"1968-","publisher":"Karger"}],"pubHistory":["Vol. 25, no. 1 (1968)-"],"id":{"issn":["1423-0356"],"eki":["26551035X"],"zdb":["1464419-8"]},"recId":"26551035X"}],"physDesc":[{"extent":"17 S."}],"language":["eng"],"origin":[{"dateIssuedDisp":"2018","dateIssuedKey":"2018"}]} | ||
| SRT | |a WANGZHENGKGASTROESOP2018 | ||