Recent developments in the research on biomarkers of cholangiocarcinoma in primary sclerosing cholangitis
Primary sclerosing cholangitis (PSC) is characterized by a chronic inflammatory process of the bile ducts of unclear aetiology. It is often complicated by cholangiocarcinoma (CCA) with a dismal prognosis. Early detection of CCA is important because treatment options for advanced disease are limited....
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2019
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| In: |
Clinics and research in hepatology and gastroenterology
Year: 2018, Jahrgang: 43, Heft: 3, Pages: 236-243 |
| ISSN: | 2210-741X |
| DOI: | 10.1016/j.clinre.2018.08.013 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1016/j.clinre.2018.08.013
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| Verfasserangaben: | Andreas Wannhoff, Daniel N. Gotthardt |
| Zusammenfassung: | Primary sclerosing cholangitis (PSC) is characterized by a chronic inflammatory process of the bile ducts of unclear aetiology. It is often complicated by cholangiocarcinoma (CCA) with a dismal prognosis. Early detection of CCA is important because treatment options for advanced disease are limited. Besides the established markers, like CA19-9, recent developments have been made using latest technologies. This review summarizes the recent advances and remaining limitations of biomarkers of CCA in PSC. |
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| Beschreibung: | Available online 25 September 2018 Gesehen am 24.06.2019 |
| Beschreibung: | Online Resource |
| ISSN: | 2210-741X |
| DOI: | 10.1016/j.clinre.2018.08.013 |