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Impact of c-MYC expression on proliferation, differentiation, and risk of neoplastic transformation of human mesenchymal stromal cells

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Mesenchymal stromal cells isolated from bone marrow (MSC) represent an attractive source of adult stem cells for regenerative medicine. However, thorough research is required into their clinical application safety issues concerning a risk of potential neoplastic degeneration in a process of MSC prop...

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Main Authors: Melnik, Svitlana (Author) , Boeuf, Stephane (Author) , Richter, Wiltrud (Author)
Format: Article (Journal)
Language:English
Published: 5 March 2019
In: Stem cell research & therapy
Year: 2019, Volume: 10, Pages: 1-18
ISSN:1757-6512
DOI:10.1186/s13287-019-1187-z
Online Access:Verlag, Volltext: https://doi.org/10.1186/s13287-019-1187-z
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Author Notes:Svitlana Melnik, Nadine Werth, Stephane Boeuf, Eva-Maria Hahn, Tobias Gotterbarm, Martina Anton and Wiltrud Richter
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Impact of c-MYC expression on proliferation, differentiation, and risk of neoplastic transformation of human mesenchymal stromal cells by Melnik, Svitlana (Author) , Werth, Nadine (Author) , Boeuf, Stephane (Author) , Hahn, Eva-Maria (Author) , Gotterbarm, Tobias (Author) , Richter, Wiltrud (Author) ,

BioMed Central 13 Mai 2019 Universitätsbibliothek Heidelberg 13 Mai 2019

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