Impact of c-MYC expression on proliferation, differentiation, and risk of neoplastic transformation of human mesenchymal stromal cells

Mesenchymal stromal cells isolated from bone marrow (MSC) represent an attractive source of adult stem cells for regenerative medicine. However, thorough research is required into their clinical application safety issues concerning a risk of potential neoplastic degeneration in a process of MSC prop...

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Hauptverfasser:	Melnik, Svitlana (VerfasserIn) , Boeuf, Stephane (VerfasserIn) , Richter, Wiltrud (VerfasserIn)
Dokumenttyp:	Article (Journal)
Sprache:	Englisch
Veröffentlicht:	5 March 2019
In:	Stem cell research & therapy Year: 2019, Jahrgang: 10, Pages: 1-18
ISSN:	1757-6512
DOI:	10.1186/s13287-019-1187-z
Online-Zugang:	Verlag, Volltext: https://doi.org/10.1186/s13287-019-1187-z
Verfasserangaben:	Svitlana Melnik, Nadine Werth, Stephane Boeuf, Eva-Maria Hahn, Tobias Gotterbarm, Martina Anton and Wiltrud Richter

Impact of c-MYC expression on proliferation, differentiation, and risk of neoplastic transformation of human mesenchymal stromal cells von Melnik, Svitlana (VerfasserIn) , Werth, Nadine (VerfasserIn) , Boeuf, Stephane (VerfasserIn) , Hahn, Eva-Maria (VerfasserIn) , Gotterbarm, Tobias (VerfasserIn) , Richter, Wiltrud (VerfasserIn) ,

BioMed Central 13 Mai 2019 Universitätsbibliothek Heidelberg 13 Mai 2019

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Impact of c-MYC expression on proliferation, differentiation, and risk of neoplastic transformation of human mesenchymal stromal cells

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