A microfluidics platform for combinatorial drug screening on cancer biopsies
Cancer patients exhibit specific sensitivities toward drug combinations that cannot be easily predicted. Here the authors setup a microfluidic platform that allows testing of multiple drug combinations correctly predicting sensitivity in vivo and they use it on patients biopsies to define effective...
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| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
22 June 2018
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| In: |
Nature Communications
Year: 2018, Jahrgang: 9 |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-018-04919-w |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1038/s41467-018-04919-w Verlag, Volltext: https://www.nature.com/articles/s41467-018-04919-w 
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| Verfasserangaben: | Federica Eduati, Ramesh Utharala, Dharanija Madhavan, Ulf Peter Neumann, Thomas Longerich, Thorsten Cramer, Julio Saez-Rodriguez, Christoph A. Merten |
| Zusammenfassung: | Cancer patients exhibit specific sensitivities toward drug combinations that cannot be easily predicted. Here the authors setup a microfluidic platform that allows testing of multiple drug combinations correctly predicting sensitivity in vivo and they use it on patients biopsies to define effective drugs. |
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| Beschreibung: | Gesehen am 22.07.2019 |
| Beschreibung: | Online Resource |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-018-04919-w |