A signal to condense
Phase separation underlies the formation of cellular membrane-less organelles. A new report identifies deacetylation at lysine residues of intrinsically disordered protein regions to drive liquid droplet formation in vitro and stress granule maturation inside cells.
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| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2019
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| In: |
Nature chemical biology
Year: 2018, Volume: 15, Issue: 1, Pages: 5-6 |
| ISSN: | 1552-4469 |
| DOI: | 10.1038/s41589-018-0179-0 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1038/s41589-018-0179-0 Verlag, Volltext: https://www.nature.com/articles/s41589-018-0179-0 |
| Author Notes: | Alessia Ruggieri and Georg Stoecklin |
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