A signal to condense
Phase separation underlies the formation of cellular membrane-less organelles. A new report identifies deacetylation at lysine residues of intrinsically disordered protein regions to drive liquid droplet formation in vitro and stress granule maturation inside cells.
Gespeichert in:
| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2019
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| In: |
Nature chemical biology
Year: 2018, Jahrgang: 15, Heft: 1, Pages: 5-6 |
| ISSN: | 1552-4469 |
| DOI: | 10.1038/s41589-018-0179-0 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1038/s41589-018-0179-0 Verlag, Volltext: https://www.nature.com/articles/s41589-018-0179-0 |
| Verfasserangaben: | Alessia Ruggieri and Georg Stoecklin |
| Zusammenfassung: | Phase separation underlies the formation of cellular membrane-less organelles. A new report identifies deacetylation at lysine residues of intrinsically disordered protein regions to drive liquid droplet formation in vitro and stress granule maturation inside cells. |
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| Beschreibung: | Published online: 10 December 2018 Gesehen am 23.07.2019 |
| Beschreibung: | Online Resource |
| ISSN: | 1552-4469 |
| DOI: | 10.1038/s41589-018-0179-0 |