Effect and safety of treatment with ACE-inhibitor Enalapril and β-blocker metoprolol on the onset of left ventricular dysfunction in Duchenne muscular dystrophy: a randomized, double-blind, placebo-controlled trial

X-linked Duchenne muscular dystrophy (DMD), the most frequent human hereditary skeletal muscle myopathy, inevitably leads to progressive dilated cardiomyopathy. We assessed the effect and safety of a combined treatment with the ACE-inhibitor enalapril and the β-blocker metoprolol in a German cohort...

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Main Authors:	Dittrich, Sven (Author) , Pattathu, Joseph George (Author) , Ebinger, Friedrich (Author) , Eichhorn, Joachim (Author) , Motz, Reinald (Author) , Korenke, Christoph (Author) , Freund, Matthias (Author) , Schumacher, Michael (Author)
Format:	Article (Journal)
Language:	English
Published:	10 May 2019
In:	Orphanet journal of rare diseases Year: 2019, Volume: 14, Pages: 1-13
ISSN:	1750-1172
DOI:	10.1186/s13023-019-1066-9
Online Access:	Verlag, Volltext: https://doi.org/10.1186/s13023-019-1066-9 Resolving-System, kostenfrei: https://doi.org/10.1186/s13023-019-1066-9
Author Notes:	Sven Dittrich, Erika Graf, Regina Trollmann, Ulrich Neudorf, Ulrike Schara, Antje Heilmann, Maja von der Hagen, Brigitte Stiller, Janbernd Kirschner, Robert Dalla Pozza, Wolfgang Müller-Felber, Katja Weiss, Katja von Au, Markus Khalil, Reinald Motz, Christoph Korenke, Martina Lange, Ekkehard Wilichowski, Joseph Pattathu, Friedrich Ebinger, Nicola Wiechmann, Rolf Schröder, Julia Halbfass, Jasmin Webinger, Anja Weise, Franz Herrndobler, Mateja Nerad, Amira Shabaiek, Güler Akin-Erdinc, Verena Greim, Dorothée Böcker, Stefanie Siepe, Sabine Schneider-Fuchs, Brigitte Egenhofer-Kummert, Barbara Burkhardt, Elena Neumann, Rudolf Korinthenberg, Christian Apitz, Matthias Freund, Michael Schumacher, Verena Gravenhorst, Daniela Deppe, Joachim Eichhorn and on behalf of the German Competence Network for Congenital Heart Defects and the Treat-NMD Neuromuscular Network Investigators list of additional local Investigators and co-workers of the German Competence Network for Congenital Heart Defects and the Treat-NMD Neuromuscular Network

Effect and safety of treatment with ACE-inhibitor Enalapril and β-blocker metoprolol on the onset of left ventricular dysfunction in Duchenne muscular dystrophy - a randomized, dou... by Dittrich, Sven (Author) , Pattathu, Joseph George (Author) , Ebinger, Friedrich (Author) ,

BioMed Central 01 Aug. 2019 Universitätsbibliothek Heidelberg 01 Aug. 2019

Article (Journal) Online Resource

Effect and safety of treatment with ACE-inhibitor Enalapril and β-blocker metoprolol on the onset of left ventricular dysfunction in Duchenne muscular dystrophy: a randomized, double-blind, placebo-controlled trial

Effect and safety of treatment with ACE-inhibitor Enalapril and β-blocker metoprolol on the onset of left ventricular dysfunction in Duchenne muscular dystrophy - a randomized, dou... by Dittrich, Sven (Author) , Pattathu, Joseph George (Author) , Ebinger, Friedrich (Author) ,

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