Asymptomatic carotid stenosis: intervention or best medical therapy?

Purpose of ReviewProvide a current overview regarding the optimal strategy for managing patients with asymptomatic carotid artery stenosis.Recent FindingsCarotid endarterectomy (CEA) and carotid artery stenting (CAS) reduce long-term stroke risk in asymptomatic patients. However, CAS is associated w...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Gaba, Kamran (VerfasserIn) , Ringleb, Peter A. (VerfasserIn) , Halliday, Alison (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 24 September 2018
In: Current neurology and neuroscience reports
Year: 2018, Jahrgang: 18, Pages: 80
ISSN:1534-6293
DOI:10.1007/s11910-018-0888-5
Online-Zugang:Verlag, Volltext: https://doi.org/10.1007/s11910-018-0888-5
Volltext
Verfasserangaben:Kamran Gaba, Peter A. Ringleb, Alison Halliday

MARC

LEADER 00000caa a2200000 c 4500
001 1670435628
003 DE-627
005 20220816201915.0
007 cr uuu---uuuuu
008 190801s2018 xx |||||o 00| ||eng c
024 7 |a 10.1007/s11910-018-0888-5  |2 doi 
035 |a (DE-627)1670435628 
035 |a (DE-599)KXP1670435628 
035 |a (OCoLC)1341235223 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Gaba, Kamran  |e VerfasserIn  |0 (DE-588)1191925145  |0 (DE-627)167043348X  |4 aut 
245 1 0 |a Asymptomatic carotid stenosis  |b intervention or best medical therapy?  |c Kamran Gaba, Peter A. Ringleb, Alison Halliday 
264 1 |c 24 September 2018 
300 |a 9 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 01.08.2019 
520 |a Purpose of ReviewProvide a current overview regarding the optimal strategy for managing patients with asymptomatic carotid artery stenosis.Recent FindingsCarotid endarterectomy (CEA) and carotid artery stenting (CAS) reduce long-term stroke risk in asymptomatic patients. However, CAS is associated with a higher risk of peri-procedural stroke. Improvements in best medical therapy (BMT) have renewed uncertainty regarding the extent to which results from older randomised controlled trials (RCTs) comparing outcomes following carotid intervention can be generalised to modern medical practise.Summary‘Average surgical risk’ patients with an asymptomatic carotid artery stenosis of 60-99% and increased risk of late stroke should be considered for either CEA or CAS. In patients deemed ‘high risk’ for surgery, CAS is indicated. Use of an anti-platelet, anti-hypertensive and statin, with strict glycaemic control, is recommended. Results from ongoing large, multicentre RCTs comparing CEA, CAS and BMT will provide clarity regarding the optimal management of patients with asymptomatic carotid artery stenosis. 
650 4 |a Asymptomatic 
650 4 |a Best medical therapy 
650 4 |a Carotid artery stenosis 
650 4 |a Carotid artery stenting 
650 4 |a Carotid endarterectomy 
700 1 |a Ringleb, Peter A.  |e VerfasserIn  |0 (DE-588)1032676175  |0 (DE-627)73863364X  |0 (DE-576)172917743  |4 aut 
700 1 |a Halliday, Alison  |e VerfasserIn  |0 (DE-588)1191926311  |0 (DE-627)1670435040  |4 aut 
773 0 8 |i Enthalten in  |t Current neurology and neuroscience reports  |d Philadelphia, Pa. : Current Science Inc., 2001  |g 18(2018) Artikel-Nummer 80, 9 Seiten  |h Online-Ressource  |w (DE-627)35716833X  |w (DE-600)2094171-7  |w (DE-576)306830663  |x 1534-6293  |7 nnas  |a Asymptomatic carotid stenosis intervention or best medical therapy? 
773 1 8 |g volume:18  |g year:2018  |g pages:80  |g extent:9  |a Asymptomatic carotid stenosis intervention or best medical therapy? 
856 4 0 |u https://doi.org/10.1007/s11910-018-0888-5  |x Verlag  |x Resolving-System  |3 Volltext 
951 |a AR 
992 |a 20190801 
993 |a Article 
994 |a 2018 
998 |g 1032676175  |a Ringleb, Peter A.  |m 1032676175:Ringleb, Peter A.  |d 910000  |d 911100  |e 910000PR1032676175  |e 911100PR1032676175  |k 0/910000/  |k 1/910000/911100/  |p 2 
999 |a KXP-PPN1670435628  |e 3502432643 
BIB |a Y 
SER |a journal 
JSO |a {"language":["eng"],"id":{"eki":["1670435628"],"doi":["10.1007/s11910-018-0888-5"]},"type":{"bibl":"article-journal","media":"Online-Ressource"},"origin":[{"dateIssuedDisp":"24 September 2018","dateIssuedKey":"2018"}],"person":[{"role":"aut","display":"Gaba, Kamran","family":"Gaba","given":"Kamran"},{"display":"Ringleb, Peter A.","family":"Ringleb","given":"Peter A.","role":"aut"},{"role":"aut","given":"Alison","display":"Halliday, Alison","family":"Halliday"}],"title":[{"title_sort":"Asymptomatic carotid stenosis","title":"Asymptomatic carotid stenosis","subtitle":"intervention or best medical therapy?"}],"physDesc":[{"extent":"9 S."}],"relHost":[{"disp":"Asymptomatic carotid stenosis intervention or best medical therapy?Current neurology and neuroscience reports","pubHistory":["1.2001 -"],"recId":"35716833X","note":["Fortsetzung der Druck-Ausgabe","Gesehen am 30.10.13"],"origin":[{"publisherPlace":"Philadelphia, Pa.","dateIssuedDisp":"2001-","publisher":"Current Science Inc.","dateIssuedKey":"2001"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"id":{"eki":["35716833X"],"issn":["1534-6293"],"zdb":["2094171-7"]},"language":["eng"],"title":[{"title_sort":"Current neurology and neuroscience reports","title":"Current neurology and neuroscience reports"}],"physDesc":[{"extent":"Online-Ressource"}],"part":{"volume":"18","extent":"9","year":"2018","text":"18(2018) Artikel-Nummer 80, 9 Seiten","pages":"80"}}],"name":{"displayForm":["Kamran Gaba, Peter A. Ringleb, Alison Halliday"]},"recId":"1670435628","note":["Gesehen am 01.08.2019"]} 
SRT |a GABAKAMRANASYMPTOMAT2420