Immunotherapy of melanoma
Arising from melanocytes in skin, mucosal membranes, eye, and meninges, melanoma is a tumor that has been associated with poor prognosis in advanced disease stages. Given the poor response to chemotherapy and radiation therapy, new treatment approaches with targeted therapy, immunotherapy, and adopt...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
May 25, 2016
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| In: |
Oncology research and treatment
Year: 2016, Jahrgang: 39, Heft: 6, Pages: 369-376 |
| ISSN: | 2296-5262 |
| DOI: | 10.1159/000446716 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1159/000446716 Verlag, Volltext: https://www.karger.com/Article/FullText/446716 |
| Verfasserangaben: | Carolin Bender, Jessica C. Hassel, Alexander Enk |
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| 520 | |a Arising from melanocytes in skin, mucosal membranes, eye, and meninges, melanoma is a tumor that has been associated with poor prognosis in advanced disease stages. Given the poor response to chemotherapy and radiation therapy, new treatment approaches with targeted therapy, immunotherapy, and adoptive T-cell therapy have revolutionized the standard of care for patients with advanced melanoma. This review provides a short overview of past, present, and future immunotherapeutic approaches and their limitations, with a focus on new combination agents in early clinical trials. | ||
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