Negative symptoms and their association with depressive symptoms in the long-term course of schizophrenia
Depressive symptoms abound in schizophrenia and even in subclinical states of the disorder. We studied the frequency of these symptoms and their relationship to negative symptoms from the first psychotic episode on over a long-term course of 134 months on data for 107 patients in our ABC Schizophren...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
23 April 2016
|
| In: |
European archives of psychiatry and clinical neuroscience
Year: 2016, Volume: 266, Issue: 5, Pages: 387-396 |
| ISSN: | 1433-8491 |
| DOI: | 10.1007/s00406-016-0697-2 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1007/s00406-016-0697-2
|
| Author Notes: | Wolfram an der Heiden, Anne Leber, Heinz Häfner |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 167192844X | ||
| 003 | DE-627 | ||
| 005 | 20220816213839.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 190823s2016 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00406-016-0697-2 |2 doi | |
| 035 | |a (DE-627)167192844X | ||
| 035 | |a (DE-599)KXP167192844X | ||
| 035 | |a (OCoLC)1341238277 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Heiden, Wolfram an der |e VerfasserIn |0 (DE-588)1153091305 |0 (DE-627)1014496667 |0 (DE-576)500075646 |4 aut | |
| 245 | 1 | 0 | |a Negative symptoms and their association with depressive symptoms in the long-term course of schizophrenia |c Wolfram an der Heiden, Anne Leber, Heinz Häfner |
| 264 | 1 | |c 23 April 2016 | |
| 300 | |a 10 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 23.08.2019 | ||
| 520 | |a Depressive symptoms abound in schizophrenia and even in subclinical states of the disorder. We studied the frequency of these symptoms and their relationship to negative symptoms from the first psychotic episode on over a long-term course of 134 months on data for 107 patients in our ABC Schizophrenia Study. Prevalence rates of 90 % for presenting at least one negative symptom and of 60 % for presenting at least one depressive symptom in the first psychotic episode illustrate the frequency of these syndromes. After the remission of psychosis the rates fell to 50 % (negative symptoms) and 40 % (depressive symptoms) over a period of 5 years, remaining stable thereafter. After we broke the negative syndrome down into (SANS) subsyndromes, a positive association emerged between anhedonia and depressive symptoms and remained stable over the entire period studied. In contrast, the association between abulia and depression grew increasingly pronounced over the illness course. However, a more detailed look revealed this to be the case in female patients only, whereas male patients showed no such association of these symptom dimensions. We have no explanation at hand for this sex difference yet. | ||
| 650 | 4 | |a Depressive symptoms | |
| 650 | 4 | |a Long-term course | |
| 650 | 4 | |a Negative symptoms | |
| 650 | 4 | |a Schizophrenia | |
| 650 | 4 | |a Sex differences | |
| 700 | 1 | |a Leber, Anne |e VerfasserIn |0 (DE-588)1193288959 |0 (DE-627)1671928172 |4 aut | |
| 700 | 1 | |a Häfner, Heinz |d 1926-2022 |e VerfasserIn |0 (DE-588)122091035 |0 (DE-627)705768597 |0 (DE-576)161261175 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t European archives of psychiatry and clinical neuroscience |d Darmstadt : Steinkopff, 1868 |g 266(2016), 5, Seite 387-396 |h Online-Ressource |w (DE-627)253722691 |w (DE-600)1459045-1 |w (DE-576)072372559 |x 1433-8491 |7 nnas |a Negative symptoms and their association with depressive symptoms in the long-term course of schizophrenia |
| 773 | 1 | 8 | |g volume:266 |g year:2016 |g number:5 |g pages:387-396 |g extent:10 |a Negative symptoms and their association with depressive symptoms in the long-term course of schizophrenia |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00406-016-0697-2 |x Verlag |x Resolving-System |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20190823 | ||
| 993 | |a Article | ||
| 994 | |a 2016 | ||
| 998 | |g 122091035 |a Häfner, Heinz |m 122091035:Häfner, Heinz |d 60000 |e 60000PH122091035 |k 0/60000/ |p 3 |y j | ||
| 999 | |a KXP-PPN167192844X |e 3508306054 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"part":{"extent":"10","issue":"5","text":"266(2016), 5, Seite 387-396","year":"2016","pages":"387-396","volume":"266"},"origin":[{"dateIssuedDisp":"1868-","publisher":"Steinkopff ; Springer","publisherPlace":"Darmstadt ; Berlin ; Heidelberg","dateIssuedKey":"1868"}],"pubHistory":["1.1868/69 -"],"disp":"Negative symptoms and their association with depressive symptoms in the long-term course of schizophreniaEuropean archives of psychiatry and clinical neuroscience","type":{"media":"Online-Ressource","bibl":"periodical"},"note":["Zusatz teils: official organ of the German Society for Biological Psychiatry","Ungezählte Beil.: Supplement"],"title":[{"title":"European archives of psychiatry and clinical neuroscience","title_sort":"European archives of psychiatry and clinical neuroscience"}],"recId":"253722691","titleAlt":[{"title":"Psychiatry and clinical neuroscience"},{"title":"Archiv für Psychiatrie und Nervenkrankheiten"},{"title":"European archives of psychiatry and neurological sciences"}],"id":{"issn":["1433-8491"],"zdb":["1459045-1"],"eki":["253722691"]},"language":["eng"],"physDesc":[{"extent":"Online-Ressource"}]}],"name":{"displayForm":["Wolfram an der Heiden, Anne Leber, Heinz Häfner"]},"origin":[{"dateIssuedKey":"2016","dateIssuedDisp":"23 April 2016"}],"person":[{"roleDisplay":"VerfasserIn","family":"Heiden","display":"Heiden, Wolfram an der","role":"aut","given":"Wolfram an der"},{"roleDisplay":"VerfasserIn","family":"Leber","display":"Leber, Anne","role":"aut","given":"Anne"},{"family":"Häfner","display":"Häfner, Heinz","roleDisplay":"VerfasserIn","role":"aut","given":"Heinz"}],"title":[{"title":"Negative symptoms and their association with depressive symptoms in the long-term course of schizophrenia","title_sort":"Negative symptoms and their association with depressive symptoms in the long-term course of schizophrenia"}],"note":["Gesehen am 23.08.2019"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"physDesc":[{"extent":"10 S."}],"id":{"eki":["167192844X"],"doi":["10.1007/s00406-016-0697-2"]},"language":["eng"],"recId":"167192844X"} | ||
| SRT | |a HEIDENWOLFNEGATIVESY2320 | ||