Cover Image

Acute mountain sickness is not related to cerebral blood flow: a decompression chamber study

To evaluate the pathogenetic role of cerebral blood flow (CBF) changes occurring before and during the development of acute mountain sickness (AMS), peak mean middle cerebral artery flow velocities (V¯¯¯MCAV¯MCA<math display="inline" id="ML1" overflow="scroll" altimg...

Full description

Saved in:
Bibliographic Details
Main Authors: Baumgartner, Ralf W. (Author) , Spyridopoulos, Ioakim (Author) , Bärtsch, Peter (Author) , Maggiorini, Marco (Author) , Oelz, Oswald (Author)
Format: Article (Journal)
Language:English
Published: 01 May 1999
In: Journal of applied physiology
Year: 1999, Volume: 86, Issue: 5, Pages: 1578-1582
ISSN:1522-1601
DOI:10.1152/jappl.1999.86.5.1578
Online Access:Verlag, Volltext: https://doi.org/10.1152/jappl.1999.86.5.1578
Verlag, Volltext: https://www.physiology.org/doi/full/10.1152/jappl.1999.86.5.1578
Get full text
Author Notes:Ralf W. Baumgartner, Ioakim Spyridopoulos, Peter Bärtsch, Marco Maggiorini, and Oswald Oelz

MARC

LEADER 00000caa a2200000 c 4500
001 1672170710
003 DE-627
005 20220816214342.0
007 cr uuu---uuuuu
008 190827s1999 xx |||||o 00| ||eng c
024 7 |a 10.1152/jappl.1999.86.5.1578  |2 doi 
035 |a (DE-627)1672170710 
035 |a (DE-599)KXP1672170710 
035 |a (OCoLC)1341238589 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Baumgartner, Ralf W.  |d 1956-2023  |e VerfasserIn  |0 (DE-588)130428744  |0 (DE-627)501468897  |0 (DE-576)298190192  |4 aut 
245 1 0 |a Acute mountain sickness is not related to cerebral blood flow  |b a decompression chamber study  |c Ralf W. Baumgartner, Ioakim Spyridopoulos, Peter Bärtsch, Marco Maggiorini, and Oswald Oelz 
264 1 |c 01 May 1999 
300 |a 5 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 27.08.2019 
520 |a To evaluate the pathogenetic role of cerebral blood flow (CBF) changes occurring before and during the development of acute mountain sickness (AMS), peak mean middle cerebral artery flow velocities (V¯¯¯MCAV¯MCA<math display="inline" id="ML1" overflow="scroll" altimg="eq-00001.gif"><msub><mover accent="true"><mi>V</mi><mo stretchy="true">¯</mo></mover><mrow><mo>MCA</mo></mrow></msub></math>) were assessed by transcranial Doppler sonography in 10 subjects at 490-m altitude, and during three 12-min periods immediately (SA1), 3 (SA2), and 6 (SA3) h after decompression to a simulated altitude of 4,559 m. AMS cerebral scores increased from 0.16 ± 0.14 at baseline to 0.44 ± 0.31 at SA1, 1.11 ± 0.88 at SA2(P < 0.05), and 1.43 ± 1.03 at SA3(P < 0.01); correspondingly, three, seven, and eight subjects had AMS. Absolute and relativeV¯¯¯MCAV¯MCA<math display="inline" id="ML2" overflow="scroll" altimg="eq-00002.gif"><msub><mover accent="true"><mi>V</mi><mo stretchy="true">¯</mo></mover><mrow><mo>MCA</mo></mrow></msub></math> at simulated altitude, expressed as percentages of low-altitude values (%V¯¯¯MCAV¯MCA<math display="inline" id="ML3" overflow="scroll" altimg="eq-00003.gif"><msub><mover accent="true"><mi>V</mi><mo stretchy="true">¯</mo></mover><mrow><mo>MCA</mo></mrow></msub></math>), did not correlate with AMS cerebral scores. Average %V¯¯¯MCAV¯MCA<math display="inline" id="ML4" overflow="scroll" altimg="eq-00004.gif"><msub><mover accent="true"><mi>V</mi><mo stretchy="true">¯</mo></mover><mrow><mo>MCA</mo></mrow></msub></math> remained unchanged, because %V¯¯¯MCAV¯MCA<math display="inline" id="ML5" overflow="scroll" altimg="eq-00005.gif"><msub><mover accent="true"><mi>V</mi><mo stretchy="true">¯</mo></mover><mrow><mo>MCA</mo></mrow></msub></math>increased in three and remained unchanged or decreased in seven subjects at SA2 and SA3. These results suggest that CBF is not important in the pathogenesis of AMS and shows substantial interindividual differences during the first hours at simulated altitude. 
700 1 |a Spyridopoulos, Ioakim  |e VerfasserIn  |4 aut 
700 1 |a Bärtsch, Peter  |e VerfasserIn  |0 (DE-588)1068984023  |0 (DE-627)821117483  |0 (DE-576)428341179  |4 aut 
700 1 |a Maggiorini, Marco  |e VerfasserIn  |4 aut 
700 1 |a Oelz, Oswald  |e VerfasserIn  |4 aut 
773 0 8 |i Enthalten in  |t Journal of applied physiology  |d Bethesda, Md. : American Physiological Society, 1948  |g 86(1999), 5, Seite 1578-1582  |h Online-Ressource  |w (DE-627)237179792  |w (DE-600)1404365-8  |w (DE-576)075289466  |x 1522-1601  |7 nnas  |a Acute mountain sickness is not related to cerebral blood flow a decompression chamber study 
773 1 8 |g volume:86  |g year:1999  |g number:5  |g pages:1578-1582  |g extent:5  |a Acute mountain sickness is not related to cerebral blood flow a decompression chamber study 
856 4 0 |u https://doi.org/10.1152/jappl.1999.86.5.1578  |x Verlag  |x Resolving-System  |3 Volltext 
856 4 0 |u https://www.physiology.org/doi/full/10.1152/jappl.1999.86.5.1578  |x Verlag  |3 Volltext 
951 |a AR 
992 |a 20190827 
993 |a Article 
994 |a 1999 
998 |g 1068984023  |a Bärtsch, Peter  |m 1068984023:Bärtsch, Peter  |d 910000  |d 910100  |e 910000PB1068984023  |e 910100PB1068984023  |k 0/910000/  |k 1/910000/910100/  |p 3 
999 |a KXP-PPN1672170710  |e 3509038479 
BIB |a Y 
SER |a journal 
JSO |a {"recId":"1672170710","language":["eng"],"note":["Gesehen am 27.08.2019"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"title":[{"title_sort":"Acute mountain sickness is not related to cerebral blood flow","subtitle":"a decompression chamber study","title":"Acute mountain sickness is not related to cerebral blood flow"}],"person":[{"role":"aut","display":"Baumgartner, Ralf W.","roleDisplay":"VerfasserIn","given":"Ralf W.","family":"Baumgartner"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Spyridopoulos, Ioakim","given":"Ioakim","family":"Spyridopoulos"},{"role":"aut","display":"Bärtsch, Peter","roleDisplay":"VerfasserIn","given":"Peter","family":"Bärtsch"},{"roleDisplay":"VerfasserIn","display":"Maggiorini, Marco","role":"aut","family":"Maggiorini","given":"Marco"},{"family":"Oelz","given":"Oswald","roleDisplay":"VerfasserIn","display":"Oelz, Oswald","role":"aut"}],"relHost":[{"name":{"displayForm":["American Physiological Society"]},"id":{"issn":["1522-1601"],"zdb":["1404365-8"],"eki":["237179792"]},"origin":[{"publisher":"American Physiological Society","dateIssuedKey":"1948","dateIssuedDisp":"1948-","publisherPlace":"Bethesda, Md."}],"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title_sort":"Journal of applied physiology","title":"Journal of applied physiology"}],"recId":"237179792","corporate":[{"role":"isb","roleDisplay":"Herausgebendes Organ","display":"American Physiological Society"}],"language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"},"disp":"Acute mountain sickness is not related to cerebral blood flow a decompression chamber studyJournal of applied physiology","note":["Gesehen am 14.02.2020"],"part":{"volume":"86","text":"86(1999), 5, Seite 1578-1582","extent":"5","year":"1999","issue":"5","pages":"1578-1582"},"titleAlt":[{"title":"JAP online"}],"pubHistory":["1.1948 -"]}],"physDesc":[{"extent":"5 S."}],"id":{"eki":["1672170710"],"doi":["10.1152/jappl.1999.86.5.1578"]},"origin":[{"dateIssuedKey":"1999","dateIssuedDisp":"01 May 1999"}],"name":{"displayForm":["Ralf W. Baumgartner, Ioakim Spyridopoulos, Peter Bärtsch, Marco Maggiorini, and Oswald Oelz"]}} 
SRT |a BAUMGARTNEACUTEMOUNT0119 

Similar Items