Necroptosis microenvironment directs lineage commitment in liver cancer
The tumour microenvironment determines which type of liver cancer develops, with transformed hepatocytes giving rise to intrahepatic cholangiocarcinoma or hepatocellular carcinoma depending or whether they are surrounded by cells undergoing necroptosis or apoptosis.
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
12 September 2018
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| In: |
Nature
Year: 2018, Jahrgang: 562, Heft: 7725, Pages: 69-75 |
| ISSN: | 1476-4687 |
| DOI: | 10.1038/s41586-018-0519-y |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1038/s41586-018-0519-y Verlag, Volltext: https://www.nature.com/articles/s41586-018-0519-y 
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| Verfasserangaben: | Marco Seehawer, Florian Heinzmann, Luana D’Artista, Jule Harbig, Pierre-François Roux, Lisa Hoenicke, Hien Dang, Sabrina Klotz, Lucas Robinson, Grégory Doré, Nir Rozenblum, Tae-Won Kang, Rishabh Chawla, Thorsten Buch, Mihael Vucur, Mareike Roth, Johannes Zuber, Tom Luedde, Bence Sipos, Thomas Longerich, Mathias Heikenwälder, Xin Wei Wang, Oliver Bischof & Lars Zender |
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