Antibiotic prescription patterns among children younger than 5 years in Nouna District, Burkina Faso

Abstract. Understanding antibiotic use may help predict emergence of antimicrobial resistance. We evaluated antibiotic prescription trends in rural Burkina Faso, where little is known about antibiotic consumption. Antibiotic prescription data for 20 communities were extracted through record review i...

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Hauptverfasser: Sié, Ali (VerfasserIn) , Bärnighausen, Till (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 1 May 2019
In: The American journal of tropical medicine and hygiene
Year: 2019, Jahrgang: 100, Heft: 5, Pages: 1121-1124
ISSN:1476-1645
DOI:10.4269/ajtmh.18-0791
Online-Zugang:Verlag, Volltext: https://doi.org/10.4269/ajtmh.18-0791
Verlag, Volltext: http://www.ajtmh.org/content/journals/10.4269/ajtmh.18-0791
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Verfasserangaben:Ali Sié, Boubacar Coulibaly, Sawadogo Adama, Lucienne Ouermi, Clarisse Dah, Charlemagne Tapsoba, Till Bärnighausen, John Daniel Kelly, Thuy Doan, Thomas M. Lietman, Jeremy D. Keenan, Catherine E. Oldenburg

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520 |a Abstract. Understanding antibiotic use may help predict emergence of antimicrobial resistance. We evaluated antibiotic prescription trends in rural Burkina Faso, where little is known about antibiotic consumption. Antibiotic prescription data for 20 communities were extracted through record review in six primary health-care facilities serving the communities. The number of antibiotic prescriptions per child-year was calculated using population-based census data from the communities. A total of 1,444 antibiotic prescriptions were made from March to June 2017 among 3,401 children in the communities. The frequency of antibiotic prescription was 1.70 prescriptions per child-year (95% CI: 1.61-1.79). Penicillins were the most common (1.04 prescriptions per child-year, 95% CI: 1.01-1.06), followed by sulfonamides (0.69 prescriptions per child-year, 95% CI: 0.67-0.71) and macrolides (0.38 prescriptions per child-year, 95% CI: 0.37-0.40). Continued monitoring of antibiotic consumption in diverse settings will be important to understand the potential for emergence of antibiotic resistance. 
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