Quantitative self-assembly prediction yields targeted nanomedicines
Molecular simulations reveal the self-assembly of small molecules into nanoparticle drug carriers. Targeting of colon and liver cancer cells by the nanoparticles via kinase inhibitors is employed in anti-tumour therapy in vivo.
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
05 February 2018
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| In: |
Nature materials
Year: 2018, Jahrgang: 17, Heft: 4, Pages: 361-368 |
| ISSN: | 1476-4660 |
| DOI: | 10.1038/s41563-017-0007-z |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1038/s41563-017-0007-z Verlag: https://www.nature.com/articles/s41563-017-0007-z 
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| Verfasserangaben: | Yosi Shamay, Janki Shah, Mehtap Işık, Aviram Mizrachi, Josef Leibold, Darjus F. Tschaharganeh, Daniel Roxbury, Januka Budhathoki-Uprety, Karla Nawaly, James L. Sugarman, Emily Baut, Michelle R. Neiman, Megan Dacek, Kripa S. Ganesh, Darren C. Johnson, Ramya Sridharan, Karen L. Chu, Vinagolu K. Rajasekhar, Scott W. Lowe, John D. Chodera and Daniel A. Heller |
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