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Impact of cancer mutational signatures on transcription factor motifs in the human genome

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Somatic mutations in cancer genomes occur through a variety of molecular mechanisms, which contribute to different mutational patterns. To summarize these, mutational signatures have been defined using a large number of cancer genomes, and related to distinct mutagenic processes. Each cancer genome...

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Main Authors: Chan, Calvin Wing Yiu (Author) , Gu, Zuguang (Author) , Bieg, Matthias (Author) , Eils, Roland (Author) , Herrmann, Carl (Author)
Format: Article (Journal)
Language:English
Published: 20 May 2019
In: BMC medical genomics
Year: 2019, Volume: 12
ISSN:1755-8794
DOI:10.1186/s12920-019-0525-4
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12920-019-0525-4
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Author Notes:Calvin Wing Yiu Chan, Zuguang Gu, Matthias Bieg, Roland Eils, Carl Herrmann
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Impact of cancer mutational signatures on transcription factor motifs in the human genome by Chan, Calvin Wing Yiu (Author) , Gu, Zuguang (Author) , Bieg, Matthias (Author) , Eils, Roland (Author) , Herrmann, Carl (Author) ,

BioMed Central 20 May 2019 Universitätsbibliothek Heidelberg 20 May 2019

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