Impact of cancer mutational signatures on transcription factor motifs in the human genome
Somatic mutations in cancer genomes occur through a variety of molecular mechanisms, which contribute to different mutational patterns. To summarize these, mutational signatures have been defined using a large number of cancer genomes, and related to distinct mutagenic processes. Each cancer genome...
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| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
20 May 2019
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| In: |
BMC medical genomics
Year: 2019, Jahrgang: 12 |
| ISSN: | 1755-8794 |
| DOI: | 10.1186/s12920-019-0525-4 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12920-019-0525-4 |
| Verfasserangaben: | Calvin Wing Yiu Chan, Zuguang Gu, Matthias Bieg, Roland Eils, Carl Herrmann |
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Impact of cancer mutational signatures on transcription factor motifs in the human genome
BioMed Central 20 May 2019 Universitätsbibliothek Heidelberg 20 May 2019
- Resolving-System, kostenfrei, Volltext
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