CerS6-derived sphingolipids interact with Mff and promote mitochondrial fragmentation in obesity
Ectopic lipid deposition and altered mitochondrial dynamics contribute to the development of obesity and insulin resistance. However, the mechanistic …
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
May 30, 2019
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| In: |
Cell
Year: 2019, Volume: 177, Issue: 6, Pages: 1536-1552,e1-e23 |
| ISSN: | 1097-4172 |
| DOI: | 10.1016/j.cell.2019.05.008 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1016/j.cell.2019.05.008 Verlag: https://www.sciencedirect.com/science/article/pii/S0092867419305069 |
| Author Notes: | Philipp Hammerschmidt, Daniela Ostkotte, Hendrik Nolte, Mathias J. Gerl, Alexander Jais, Hanna L. Brunner, Hans-Georg Sprenger, Motoharu Awazawa, Hayley T. Nicholls, Sarah M. Turpin-Nolan, Thomas Langer, Marcus Krüger, Britta Brügger, and Jens C. Brüning |
| Summary: | Ectopic lipid deposition and altered mitochondrial dynamics contribute to the development of obesity and insulin resistance. However, the mechanistic … |
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| Item Description: | Gesehen am 08.10.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1097-4172 |
| DOI: | 10.1016/j.cell.2019.05.008 |