CerS6-derived sphingolipids interact with Mff and promote mitochondrial fragmentation in obesity

Ectopic lipid deposition and altered mitochondrial dynamics contribute to the development of obesity and insulin resistance. However, the mechanistic …

Saved in:
Bibliographic Details
Main Authors: Hammerschmidt, Philipp (Author) , Schweinfurth, Daniela (Author) , Brügger, Britta (Author)
Format: Article (Journal)
Language:English
Published: May 30, 2019
In: Cell
Year: 2019, Volume: 177, Issue: 6, Pages: 1536-1552,e1-e23
ISSN:1097-4172
DOI:10.1016/j.cell.2019.05.008
Online Access:Verlag, Volltext: https://doi.org/10.1016/j.cell.2019.05.008
Verlag: https://www.sciencedirect.com/science/article/pii/S0092867419305069
Get full text
Author Notes:Philipp Hammerschmidt, Daniela Ostkotte, Hendrik Nolte, Mathias J. Gerl, Alexander Jais, Hanna L. Brunner, Hans-Georg Sprenger, Motoharu Awazawa, Hayley T. Nicholls, Sarah M. Turpin-Nolan, Thomas Langer, Marcus Krüger, Britta Brügger, and Jens C. Brüning
Description
Summary:Ectopic lipid deposition and altered mitochondrial dynamics contribute to the development of obesity and insulin resistance. However, the mechanistic …
Item Description:Gesehen am 08.10.2019
Physical Description:Online Resource
ISSN:1097-4172
DOI:10.1016/j.cell.2019.05.008