Correlates of aggression in personality disorders: an update

Purpose of ReviewThis review article aims at giving an update on studies investigating correlates of aggression in personality disorders during the last 5 years.Recent FindingsMost data refer to borderline personality disorder (BPD) and antisocial personality disorder (ASPD). In BPD, emotion dysregu...

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Main Authors: Mancke, Falk (Author) , Herpertz, Sabine (Author) , Bertsch, Katja (Author)
Format: Article (Journal)
Language:English
Published: [August 2018]
In: Current psychiatry reports
Year: 2018, Volume: 20, Issue: 8
ISSN:1535-1645
DOI:10.1007/s11920-018-0929-4
Online Access:Verlag, Volltext: https://doi.org/10.1007/s11920-018-0929-4
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Author Notes:Falk Mancke, Sabine C. Herpertz, Katja Bertsch

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520 |a Purpose of ReviewThis review article aims at giving an update on studies investigating correlates of aggression in personality disorders during the last 5 years.Recent FindingsMost data refer to borderline personality disorder (BPD) and antisocial personality disorder (ASPD). In BPD, emotion dysregulation, hypersensitivity to interpersonal rejection/threat, increased rumination, increased negative urgency, aggression-related knowledge structures, and invalidation were either corroborated or emerged as psychological correlates of aggression, while reduced ambiguity sensitivity, hyposensitivity to interpersonal threat, and reduced mindfulness were associated with aggression in ASPD. Neurobiologically, alterations of the monoaminooxidase-A-, the oxytocinergic-, and the prefrontal-limbic-system as well as increases of the thyroid hormone T3, γ-aminobutyric acid and several inflammatory markers were associated with increased aggression across various personality disorders.SummaryOur understanding of correlates of aggression in personality disorders has increased over the last 5 years. More efforts in improving the conceptualization of personality disorders and aggression are needed to develop innovative treatments for those affected. 
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