Virtues of volatility: a facile transesterification approach to boronic acids
Boronic acids are an increasingly important compound class for many applications, including C-C bond formation reactions, medicinal chemistry, and diagnostics. The deprotection of boronic ester intermediates is frequently a problematic and inefficient step in boronic acid syntheses. We describe an a...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
April 23, 2019
|
| In: |
Organic letters
Year: 2019, Jahrgang: 21, Heft: 9, Pages: 3048-3052 |
| ISSN: | 1523-7052 |
| DOI: | 10.1021/acs.orglett.9b00584 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1021/acs.orglett.9b00584
|
| Verfasserangaben: | Stefan P.A. Hinkes, Christian D.P. Klein |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1678714305 | ||
| 003 | DE-627 | ||
| 005 | 20230426135318.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 191010s2019 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1021/acs.orglett.9b00584 |2 doi | |
| 035 | |a (DE-627)1678714305 | ||
| 035 | |a (DE-599)KXP1678714305 | ||
| 035 | |a (OCoLC)1341245270 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Hinkes, Stefan |d 1991- |e VerfasserIn |0 (DE-588)1196848262 |0 (DE-627)1678713856 |4 aut | |
| 245 | 1 | 0 | |a Virtues of volatility |b a facile transesterification approach to boronic acids |c Stefan P.A. Hinkes, Christian D.P. Klein |
| 264 | 1 | |c April 23, 2019 | |
| 300 | |a 5 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 10.10.2019 | ||
| 520 | |a Boronic acids are an increasingly important compound class for many applications, including C-C bond formation reactions, medicinal chemistry, and diagnostics. The deprotection of boronic ester intermediates is frequently a problematic and inefficient step in boronic acid syntheses. We describe an approach that highly facilitates this transformation by leveraging the volatility of methylboronic acid and its diol esters. The method is performed under mild conditions, provides high yields, and eliminates cumbersome and problematic purification steps. | ||
| 700 | 1 | |a Klein, Christian D. |e VerfasserIn |0 (DE-588)1060644894 |0 (DE-627)800410157 |0 (DE-576)416768717 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Organic letters |d Washington, DC : ACS, 1999 |g 21(2019), 9, Seite 3048-3052 |h Online-Ressource |w (DE-627)306717662 |w (DE-600)1501522-1 |w (DE-576)082438013 |x 1523-7052 |7 nnas |a Virtues of volatility a facile transesterification approach to boronic acids |
| 773 | 1 | 8 | |g volume:21 |g year:2019 |g number:9 |g pages:3048-3052 |g extent:5 |a Virtues of volatility a facile transesterification approach to boronic acids |
| 856 | 4 | 0 | |u https://doi.org/10.1021/acs.orglett.9b00584 |x Verlag |x Resolving-System |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20191010 | ||
| 993 | |a Article | ||
| 994 | |a 2019 | ||
| 998 | |g 1060644894 |a Klein, Christian D. |m 1060644894:Klein, Christian D. |d 160000 |d 160100 |e 160000PK1060644894 |e 160100PK1060644894 |k 0/160000/ |k 1/160000/160100/ |p 2 |y j | ||
| 998 | |g 1196848262 |a Hinkes, Stefan |m 1196848262:Hinkes, Stefan |d 160000 |d 160100 |e 160000PH1196848262 |e 160100PH1196848262 |k 0/160000/ |k 1/160000/160100/ |p 1 |x j | ||
| 999 | |a KXP-PPN1678714305 |e 3521440346 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"type":{"media":"Online-Ressource","bibl":"article-journal"},"language":["eng"],"note":["Gesehen am 10.10.2019"],"title":[{"title":"Virtues of volatility","title_sort":"Virtues of volatility","subtitle":"a facile transesterification approach to boronic acids"}],"origin":[{"dateIssuedKey":"2019","dateIssuedDisp":"April 23, 2019"}],"person":[{"display":"Hinkes, Stefan","family":"Hinkes","role":"aut","given":"Stefan"},{"given":"Christian D.","role":"aut","family":"Klein","display":"Klein, Christian D."}],"relHost":[{"name":{"displayForm":["American Chemical Society"]},"pubHistory":["1.1999 -"],"id":{"eki":["306717662"],"issn":["1523-7052"],"zdb":["1501522-1"]},"part":{"extent":"5","text":"21(2019), 9, Seite 3048-3052","issue":"9","pages":"3048-3052","volume":"21","year":"2019"},"recId":"306717662","physDesc":[{"extent":"Online-Ressource"}],"disp":"Virtues of volatility a facile transesterification approach to boronic acidsOrganic letters","origin":[{"dateIssuedDisp":"1999-","dateIssuedKey":"1999","publisherPlace":"Washington, DC","publisher":"ACS"}],"title":[{"title":"Organic letters","title_sort":"Organic letters"}],"language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"},"note":["Gesehen am 25.08.2020"]}],"physDesc":[{"extent":"5 S."}],"recId":"1678714305","id":{"doi":["10.1021/acs.orglett.9b00584"],"eki":["1678714305"]},"name":{"displayForm":["Stefan P.A. Hinkes, Christian D.P. Klein"]}} | ||
| SRT | |a HINKESSTEFVIRTUESOFV2320 | ||