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Dual role of USP30 in controlling basal pexophagy and mitophagy

Abstract USP30 is an integral protein of the outer mitochondrial membrane that counteracts PINK1 and Parkin-dependent mitophagy following acute mitochondrial depolarisation. Here, we use two distinct mitophagy reporter systems to reveal tonic suppression by USP30, of a PINK1-dependent component of b...

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Main Authors: Marcassa, Elena (Author) , Kallinos, Andreas (Author) , Jardine, Jane (Author) , Rusilowicz-Jones, Emma V (Author) , Martinez, Aitor (Author) , Kühl, Sandra (Author) , Islinger, Markus (Author) , Clague, Michael J (Author) , Urbé, Sylvie (Author)
Format: Article (Journal)
Language:English
Published: [1 July 2018]
In: EMBO reports
Year: 2018, Volume: 19, Issue: 7
ISSN:1469-3178
DOI:10.15252/embr.201745595
Online Access:Verlag, Volltext: https://doi.org/10.15252/embr.201745595
Verlag, Volltext: https://www.embopress.org/doi/full/10.15252/embr.201745595
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Author Notes:Elena Marcassa, Andreas Kallinos, Jane Jardine, Emma V. Rusilowicz-Jones, Aitor Martinez, Sandra Kuehl, Markus Islinger, Michael J Clague & Sylvie Urbé

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