Assessing the lifetime cost-effectiveness of low-protein infant formula as early obesity prevention strategy: The CHOP Randomized Trial
Background: Although there is a growing number of early childhood obesity prevention programs, only a few of them are effective in the long run. Even fewer reports exist on lifetime cost-effectiveness of early prevention strategies. This paper aimed to assess the lifetime cost-effectiveness of infan...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
19 July 2019
|
| In: |
Nutrients
Year: 2019, Jahrgang: 11, Heft: 7 |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu11071653 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.3390/nu11071653 Verlag, kostenfrei, Volltext: https://www.mdpi.com/2072-6643/11/7/1653 
|
| Verfasserangaben: | Diana Sonntag, Freia De Bock, Martina Totzauer and Berthold Koletzko |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1679074229 | ||
| 003 | DE-627 | ||
| 005 | 20210817004701.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 191017s2019 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3390/nu11071653 |2 doi | |
| 035 | |a (DE-627)1679074229 | ||
| 035 | |a (DE-599)KXP1679074229 | ||
| 035 | |a (OCoLC)1264105500 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Sonntag, Diana |e VerfasserIn |0 (DE-588)138676534 |0 (DE-627)604737181 |0 (DE-576)308554698 |4 aut | |
| 245 | 1 | 0 | |a Assessing the lifetime cost-effectiveness of low-protein infant formula as early obesity prevention strategy |b The CHOP Randomized Trial |c Diana Sonntag, Freia De Bock, Martina Totzauer and Berthold Koletzko |
| 264 | 1 | |c 19 July 2019 | |
| 300 | |a 11 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 17.10.2019 | ||
| 520 | |a Background: Although there is a growing number of early childhood obesity prevention programs, only a few of them are effective in the long run. Even fewer reports exist on lifetime cost-effectiveness of early prevention strategies. This paper aimed to assess the lifetime cost-effectiveness of infant feeding modification aiming at reducing risk of later obesity. Methods: The simulation model consists of two parts: (a) Model I used data from the European Childhood Obesity Project (CHOP) trial (up to 6 years) and the German Interview and Examination Survey for Children (KiGGS) (6-17 years) to evaluate BMI trajectories of infants receiving either lower protein (LP) or higher protein (HP) content formula; and (b) Model II estimated lifetime cost-effectiveness based on Model I BMI trajectories. Compared to HP formula, LP formula feeding would incur lower costs that are attributable to childhood obesity across all decades of life. Results: Our analysis showed that LP formula would be cost-effective in terms of a positive net monetary benefit (discounted 3%) as an obesity prevention strategy. For the 19% of infants fed with formula in Germany, the LP strategy would result in cost savings of € 2.5 billion. Conclusions: Our study is one of the first efforts to provide much-needed cost-effectiveness evidence of infant feeding modification, thereby potentially motivating interventionists to reassess their resource allocation. | ||
| 650 | 4 | |a childhood | |
| 650 | 4 | |a cost-effectiveness | |
| 650 | 4 | |a early nutrition | |
| 650 | 4 | |a formula | |
| 650 | 4 | |a markov model | |
| 650 | 4 | |a obesity prevention | |
| 700 | 1 | |a Bock, Freia de |d 1979- |e VerfasserIn |0 (DE-588)130051675 |0 (DE-627)488792770 |0 (DE-576)297970399 |4 aut | |
| 700 | 1 | |a Totzauer, Martina |e VerfasserIn |4 aut | |
| 700 | 1 | |a Koletzko, Berthold |d 1954- |e VerfasserIn |0 (DE-588)109717686 |0 (DE-627)537491821 |0 (DE-576)169605396 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Nutrients |d Basel : MDPI, 2009 |g 11(2019,7) Artikel-Nummer 1653, 11 Seiten |h Online-Ressource |w (DE-627)610604155 |w (DE-600)2518386-2 |w (DE-576)311829600 |x 2072-6643 |7 nnas |a Assessing the lifetime cost-effectiveness of low-protein infant formula as early obesity prevention strategy The CHOP Randomized Trial |
| 773 | 1 | 8 | |g volume:11 |g year:2019 |g number:7 |g extent:11 |a Assessing the lifetime cost-effectiveness of low-protein infant formula as early obesity prevention strategy The CHOP Randomized Trial |
| 856 | 4 | 0 | |u https://doi.org/10.3390/nu11071653 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u https://www.mdpi.com/2072-6643/11/7/1653 |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20191017 | ||
| 993 | |a Article | ||
| 994 | |a 2019 | ||
| 998 | |g 130051675 |a Bock, Freia de |m 130051675:Bock, Freia de |d 60000 |d 65300 |e 60000PB130051675 |e 65300PB130051675 |k 0/60000/ |k 1/60000/65300/ |p 2 | ||
| 998 | |g 138676534 |a Sonntag, Diana |m 138676534:Sonntag, Diana |d 60000 |d 65300 |e 60000PS138676534 |e 65300PS138676534 |k 0/60000/ |k 1/60000/65300/ |p 1 |x j | ||
| 999 | |a KXP-PPN1679074229 |e 3523521556 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"name":{"displayForm":["Molecular Diversity Preservation International (MDPI)"]},"origin":[{"dateIssuedKey":"2009","publisher":"MDPI","dateIssuedDisp":"2009-","publisherPlace":"Basel"}],"id":{"eki":["610604155"],"zdb":["2518386-2"],"issn":["2072-6643"]},"type":{"bibl":"periodical","media":"Online-Ressource"},"note":["Gesehen am 27.07.12"],"disp":"Assessing the lifetime cost-effectiveness of low-protein infant formula as early obesity prevention strategy The CHOP Randomized TrialNutrients","recId":"610604155","language":["eng"],"pubHistory":["1.2009 -"],"part":{"year":"2019","issue":"7","volume":"11","text":"11(2019,7) Artikel-Nummer 1653, 11 Seiten","extent":"11"},"title":[{"title_sort":"Nutrients","title":"Nutrients"}]}],"physDesc":[{"extent":"11 S."}],"id":{"eki":["1679074229"],"doi":["10.3390/nu11071653"]},"origin":[{"dateIssuedDisp":"19 July 2019","dateIssuedKey":"2019"}],"name":{"displayForm":["Diana Sonntag, Freia De Bock, Martina Totzauer and Berthold Koletzko"]},"recId":"1679074229","language":["eng"],"note":["Gesehen am 17.10.2019"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"title":[{"title_sort":"Assessing the lifetime cost-effectiveness of low-protein infant formula as early obesity prevention strategy","title":"Assessing the lifetime cost-effectiveness of low-protein infant formula as early obesity prevention strategy","subtitle":"The CHOP Randomized Trial"}],"person":[{"given":"Diana","family":"Sonntag","role":"aut","roleDisplay":"VerfasserIn","display":"Sonntag, Diana"},{"role":"aut","display":"Bock, Freia de","roleDisplay":"VerfasserIn","given":"Freia de","family":"Bock"},{"given":"Martina","family":"Totzauer","role":"aut","display":"Totzauer, Martina","roleDisplay":"VerfasserIn"},{"display":"Koletzko, Berthold","roleDisplay":"VerfasserIn","role":"aut","family":"Koletzko","given":"Berthold"}]} | ||
| SRT | |a SONNTAGDIAASSESSINGT1920 | ||