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Thermophile 90S pre-ribosome structures reveal the reverse order of co-transcriptional 18S rRNA subdomain integration

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Eukaryotic ribosome biogenesis involves RNA folding and processing that depend on assembly factors and small nucleolar RNAs (snoRNAs). The 90S (SSU-processome) is the earliest pre-ribosome structurally analyzed, which was suggested to assemble stepwise along the growing pre-rRNA from 5′ > 3′, but...

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Main Authors: Cheng, Jingdong (Author) , Baßler, Jochen (Author) , Fischer, Paulina (Author) , Lau, Benjamin (Author) , Kellner, Nikola (Author) , Kunze, Ruth (Author) , Griesel, Sabine (Author) , Kallas, Martina (Author) , Hurt, Ed (Author)
Format: Article (Journal)
Language:English
Published: August 1, 2019
In: Molecular cell
Year: 2019, Volume: 75, Issue: 6, Pages: 1256-1269.e1–e7
ISSN:1097-4164
DOI:10.1016/j.molcel.2019.06.032
Online Access:Verlag, Volltext: https://doi.org/10.1016/j.molcel.2019.06.032
Verlag: http://www.sciencedirect.com/science/article/pii/S1097276519304897
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Author Notes:Jingdong Cheng, Jochen Baßler, Paulina Fischer, Benjamin Lau, Nikola Kellner, Ruth Kunze, Sabine Griesel, Martina Kallas, Otto Berninghausen, Daniela Strauss, Roland Beckmann, and Ed Hurt
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Thermophile 90S pre-ribosome structures reveal the reverse order of co-transcriptional 18S rRNA subdomain integration by Cheng, Jingdong (Author) , Baßler, Jochen (Author) , Fischer, Paulina (Author) , Lau, Benjamin (Author) , Kellner, Nikola (Author) , Kunze, Ruth (Author) , Griesel, Sabine (Author) , Kallas, Martina (Author) , Strauß, Daniela (Author) , Hurt, Ed (Author) ,

Elsevier ; Cell Press 2019 Universitätsbibliothek Heidelberg 2019

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