Extending the time window for intravenous thrombolysis in acute ischemic stroke using magnetic resonance imaging-based patient selection
Background: Intravenous thrombolysis with alteplase within a time window up to 4.5 h is the only approved pharmacological treatment for acute ischemic stroke. We studied whether acute ischemic stroke patients with penumbral tissue identified on magnetic resonance imaging 4.5-9 h after symptom onset...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
April 4, 2019
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| In: |
International journal of stroke
Year: 2019, Jahrgang: 14, Heft: 5, Pages: 483-490 |
| ISSN: | 1747-4949 |
| DOI: | 10.1177/1747493019840938 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1177/1747493019840938 Verlag: http://journals.sagepub.com/doi/10.1177/1747493019840938 
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| Verfasserangaben: | Peter Ringleb, Martin Bendszus, Erich Bluhmki, Geoffrey Donnan, Christoph Eschenfelder, Marc Fatar, Christof Kessler, Carlos Molina, Didier Leys, Girish Muddegowda, Sven Poli, Peter Schellinger, Stefan Schwab, Joaquin Serena, Danilo Toni, Nils Wahlgren and Werner Hacke, for the ECASS-4 study group |
MARC
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| 520 | |a Background: Intravenous thrombolysis with alteplase within a time window up to 4.5 h is the only approved pharmacological treatment for acute ischemic stroke. We studied whether acute ischemic stroke patients with penumbral tissue identified on magnetic resonance imaging 4.5-9 h after symptom onset benefit from intravenous thrombolysis compared to placebo. | ||
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