A rare cause for lower back pain: a case of an IgG4-related periaortitis
IgG4-related disease (IgG4-RD) are a group of autoinflammatory diseases often presenting as tumor-like lesions because of their infiltrative or mass forming behavior. They are characterized by a typical histology consisting of storiform fibrosis, high numbers of infiltrating IgG4-positive plasma cel...
Gespeichert in:
| Hauptverfasser: | , , , , |
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| Weitere Verfasser: | |
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2016
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| In: |
Clinical rheumatology
Year: 2016, Jahrgang: 35, Heft: 1, Pages: 265-270 |
| ISSN: | 1434-9949 |
| DOI: | 10.1007/s10067-014-2535-0 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1007/s10067-014-2535-0 |
| Verfasserangaben: | Christian Löffler, Johannes Hoffend, Martin Rebel, Rüdiger Waldherr, Michael Uppenkamp, Raoul Bergner |
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| 245 | 1 | 2 | |a A rare cause for lower back pain |b a case of an IgG4-related periaortitis |c Christian Löffler, Johannes Hoffend, Martin Rebel, Rüdiger Waldherr, Michael Uppenkamp, Raoul Bergner |
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| 520 | |a IgG4-related disease (IgG4-RD) are a group of autoinflammatory diseases often presenting as tumor-like lesions because of their infiltrative or mass forming behavior. They are characterized by a typical histology consisting of storiform fibrosis, high numbers of infiltrating IgG4-positive plasma cells, obliterative phlebitis, and a moderate presence of eosinophilic cells. Serum IgG4 levels can be elevated. We present a case of a 57 year-old male patient with immobilizing lower back pain, fever, and night sweats. We diagnosed IgG4-related periaortitis using serum IgG4 levels, abdominal ultrasound, PET/CT, and histology. We successfully treated the patient with glucocorticoids (GC) and azathioprine. Periaortitis is a rare presentation of IgG4-RD and therefore noteworthy. It has to be considered in patients with a retroperitoneal mass. | ||
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