Drug transporters: molecular characterization and role in drug disposition
A comprehensive guide to drug transporters that influence the absorption, distribution, and elimination of drugs in the body. The development of powerful expression cloning and genome analysis techniques has facilitated the molecular identification and characterization of numerous transporters that...
Gespeichert in:
| Weitere Verfasser: | , |
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| Dokumenttyp: | Book/Monograph |
| Sprache: | Englisch |
| Veröffentlicht: |
Hoboken, N.J
Wiley-Interscience
©2007
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| Volumes / Articles: | Show Volumes / Articles. |
| DOI: | 10.1002/9780470140505 |
| Schlagworte: | |
| Online-Zugang: | Verlag: https://onlinelibrary.wiley.com/doi/book/10.1002/9780470140505 Resolving-System, John Wiley, Volltext: http://dx.doi.org/10.1002/9780470140505 Verlag, Volltext: http://onlinelibrary.wiley.com/book/10.1002/9780470140505 Verlag, Autorenbiografie: http://catdir.loc.gov/catdir/enhancements/fy0739/2006038880-b.html Verlag, Verlagsangaben: http://catdir.loc.gov/catdir/enhancements/fy0739/2006038880-d.html 
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| Verfasserangaben: | edited by Guofeng You, Marilyn E. Morris |
| Zusammenfassung: | A comprehensive guide to drug transporters that influence the absorption, distribution, and elimination of drugs in the body. The development of powerful expression cloning and genome analysis techniques has facilitated the molecular identification and characterization of numerous transporters that play a crucial role in drug disposition. Explaining the principles of drug transport and the associated techniques, Drug Transporters: Molecular Characterization and Role in Drug Disposition:.:. ;. Provides a comprehensive overview of drug transporters. ;. Includes specific descriptions of transport Drug transport in the kidney / Naohiko Anzai and Hitoshi Endou -- Drug transporters in the intestine / Yaming Su and Patrick J. Sinko -- Regulation of drug transporter activity / Mei Hong and Guofeng You -- Experimental approaches to the study of drug transporters / Yoshiyuki Kubo, Yukio Kato, and Akira Tsuji -- In vitro-in vivo scale-up of drug transport activities / Kazuya Maeda and Yuichi Sugiyama -- Age- and gender-related differences in xenobiotic transporter expression / Curtis D. Klaassen and Xingguo Cheng -- Polymorphisms of drug transporters and clinical relevance / Leslie W. Chinn, Jason M. Gow, and Deanna L. Kroetz -- Diet/nutrient interactions with drug transporters / Xiaodong Wang and Marilyn E. Morris -- Interplay of drug transporters and enzymes on hepatic drug processing / K. Sandy Pang, Huadong Sun, and Shanjun Liu -- Clinical relevance : drug-drug interactions, pharmacokinetics, pharmacodynamics, and toxicity / Serena Marchetti [and others]. Overview of drug transporter families / Guofeng You and Marilyn E. Morris -- Organic cation transporters / Thomas J. Urban and Kathleen M. Giacomini -- Organic cation/carnitine transporters / Ijaz A. Qureshi [and others] -- Organic anion transporters / Megha Nagle [and others] -- Organic anion-transporting polypeptides / Rommel G. Tirona and Richard B. Kim -- Mammalian oligopeptide transporters / Stephen M. Carl [and others] -- Monocarboxylate transporters / Justin A. Spanier and Lester R. Drewes -- Nucleoside transporters : CNTs and ENTs / Li Xia, Mingyan Zhou, and Joanne Wang -- Bile acid transporters / Jyrki J. Eloranta and Gerd A. Kullak-Ublick -- Multidrug resistance protein : P-glycoprotein / Frances J. Sharom -- Multidrug resistance proteins of the ABCC subfamily / Anne T. Nies, Maria Rius, and Dietrich Keppler -- Breast cancer resistance protein / Robert W. Robey [and others] -- Drug transport in the liver / Pieter Annaert [and others] -- Drug transport in the brain / Patrick T. Ronaldson, Karlo Babakhanian, and Reina Bendayan. |
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| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | Online Resource |
| ISBN: | 047014050X 0470140496 1280956968 9780470140505 9780470140499 9781280956966 9780471784913 0471784915 |
| DOI: | 10.1002/9780470140505 |