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Drug transporters: molecular characterization and role in drug disposition

A comprehensive guide to drug transporters that influence the absorption, distribution, and elimination of drugs in the body. The development of powerful expression cloning and genome analysis techniques has facilitated the molecular identification and characterization of numerous transporters that...

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Bibliographic Details
Other Authors: You, Guofeng (Editor) , Morris, Marilyn Emily (Editor)
Format: Book/Monograph
Language:English
Published: Hoboken, N.J Wiley-Interscience ©2007
Volumes / Articles: Show Volumes / Articles.
DOI:10.1002/9780470140505
Subjects:
Arzneistoffträger
Pharmakokinetik
Wirkstoff-Rezeptor-Bindung
Stofftransport
Arzneimittel
Online Access:Verlag: https://onlinelibrary.wiley.com/doi/book/10.1002/9780470140505
Resolving-System, John Wiley, Volltext: http://dx.doi.org/10.1002/9780470140505
Verlag, Volltext: http://onlinelibrary.wiley.com/book/10.1002/9780470140505
Verlag, Autorenbiografie: http://catdir.loc.gov/catdir/enhancements/fy0739/2006038880-b.html
Verlag, Verlagsangaben: http://catdir.loc.gov/catdir/enhancements/fy0739/2006038880-d.html
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Author Notes:edited by Guofeng You, Marilyn E. Morris
Table of Contents:
  • DRUG TRANSPORTERS; CONTENTS; Contributors; Preface; 1 Overview of Drug Transporter Families; 2 Organic Cation Transporters; 3 Organic Cation/Carnitine Transporters; 4 Organic Anion Transporters; 5 Organic Anion-Transporting Polypeptides; 6 Mammalian Oligopeptide Transporters; 7 Monocarboxylate Transporters; 8 Nucleoside Transporters: CNTs and ENTs; 9 Bile Acid Transporters; 10 Multidrug Resistance Protein: P-Glycoprotein; 11 Multidrug Resistance Proteins of the ABCC Subfamily; 12 Breast Cancer Resistance Protein; 13 Drug Transport in the Liver; 14 Drug Transport in the Brain
  • 15 Drug Transport in the Kidney16 Drug Transporters in the Intestine; 17 Regulation of Drug Transporter Activity; 18 Experimental Approaches to the Study of Drug Transporters; 19 In Vitro-In Vivo Scale-up of Drug Transport Activities; 20 Age- and Gender-Related Differences in Xenobiotic Transporter Expression; 21 Polymorphisms of Drug Transporters and Clinical Relevance; 22 Diet/Nutrient Interactions with Drug Transporters; 23 Interplay of Drug Transporters and Enzymes on Hepatic Drug Processing; 24 Clinical Relevance: Drug-Drug Interactions, Pharmacokinetics, Pharmacodynamics, and Toxicity
  • Index

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