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Identification of MALDI imaging proteolytic peptides using LC-MS/MS-based biomarker discovery data: a proof of concept

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Purpose Identification of proteolytic peptides from matrix-assisted laser desorption/ionization (MALDI) imaging remains a challenge. The low fragmentation yields obtained using in situ post source decay impairs identification. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is an alternati...

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Main Authors: Longuespée, Rémi (Author) , Kazdal, Daniel (Author) , Zgorzelski, Christiane (Author) , Kriegsmann, Katharina (Author) , Schirmacher, Peter (Author) , Fresnais, Margaux (Author) , Kriegsmann, Mark (Author)
Format: Article (Journal)
Language:English
Published: 2019
In: Proteomics. Clinical applications
Year: 2018, Volume: 13, Issue: 1
ISSN:1862-8354
DOI:10.1002/prca.201800158
Online Access:Verlag, Volltext: https://doi.org/10.1002/prca.201800158
Verlag: https://onlinelibrary.wiley.com/doi/abs/10.1002/prca.201800158
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Author Notes:Rémi Longuespée, Alice Ly, Rita Casadonte, Kristina Schwamborn, Daniel Kazdal, Christiane Zgorzelski, Christine Bollwein, Katharina Kriegsmann, Wilko Weichert, Jörg Kriegsmann, Peter Schirmacher, Margaux Fresnais, Cristiano Oliveira, and Mark Kriegsmann
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Identification of MALDI imaging proteolytic peptides using LC-MS/MS-based biomarker discovery data: a proof of concept by Longuespée, Rémi (Author) , Kazdal, Daniel (Author) , Zgorzelski, Christiane (Author) , Kriegsmann, Katharina (Author) , Schirmacher, Peter (Author) , Fresnais, Margaux (Author) , Oliveira, Cristiano (Author) , Kriegsmann, Mark (Author) ,


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