Identification of MALDI imaging proteolytic peptides using LC-MS/MS-based biomarker discovery data: a proof of concept
Purpose Identification of proteolytic peptides from matrix-assisted laser desorption/ionization (MALDI) imaging remains a challenge. The low fragmentation yields obtained using in situ post source decay impairs identification. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is an alternati...
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| Hauptverfasser: | , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2019
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| In: |
Proteomics. Clinical applications
Year: 2018, Jahrgang: 13, Heft: 1 |
| ISSN: | 1862-8354 |
| DOI: | 10.1002/prca.201800158 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1002/prca.201800158 Verlag: https://onlinelibrary.wiley.com/doi/abs/10.1002/prca.201800158 |
| Verfasserangaben: | Rémi Longuespée, Alice Ly, Rita Casadonte, Kristina Schwamborn, Daniel Kazdal, Christiane Zgorzelski, Christine Bollwein, Katharina Kriegsmann, Wilko Weichert, Jörg Kriegsmann, Peter Schirmacher, Margaux Fresnais, Cristiano Oliveira, and Mark Kriegsmann |