The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes

Continuous cycles of nucleo-cytoplasmic transport require disassembly of transport receptor-Ran-GTP complexes in the cytoplasm. Here the authors elucidate the specific function of the RanBP2 complex in the disassembly process.

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Bibliographic Details
Main Authors: Ritterhoff, Tobias (Author) , Das, Hrishikesh (Author) , Hofhaus, Götz (Author) , Schröder, Rasmus R. (Author) , Flotho, Annette (Author) , Melchior, Frauke (Author)
Format: Article (Journal)
Language:English
Published: 10 May 2016
In: Nature Communications
Year: 2016, Volume: 7
ISSN:2041-1723
DOI:10.1038/ncomms11482
Online Access:Verlag, Volltext: https://doi.org/10.1038/ncomms11482
Verlag, Volltext: https://www.nature.com/articles/ncomms11482
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Author Notes:Tobias Ritterhoff, Hrishikesh Das, Götz Hofhaus, Rasmus R. Schröder, Annette Flotho & Frauke Melchior
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Summary:Continuous cycles of nucleo-cytoplasmic transport require disassembly of transport receptor-Ran-GTP complexes in the cytoplasm. Here the authors elucidate the specific function of the RanBP2 complex in the disassembly process.
Item Description:Gesehen am 28.10.2019
Physical Description:Online Resource
ISSN:2041-1723
DOI:10.1038/ncomms11482