rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: 19F oximetry with semifluorinated alkanes
  title info:
    title: F19 oximetry with semifluorinated alkanes
  name:
    name part: Kegel, Stefan
    name part: 1983-
    role:
      role term: creator
    role:
      role term: VerfasserIn
    role:
      role term: aut
  name:
    name part: Chacón-Caldera, Jorge
    name part: 1985-
    role:
      role term: VerfasserIn
    role:
      role term: aut
  name:
    name part: Tsagogiorgas, Charalambos
    name part: 1974-
    role:
      role term: VerfasserIn
    role:
      role term: aut
  name:
    name part: Glatting, Gerhard
    name part: 1961-
    role:
      role term: VerfasserIn
    role:
      role term: aut
  name:
    name part: Schad, Lothar R.
    name part: 1956-
    role:
      role term: VerfasserIn
    role:
      role term: aut
  type of resource: text
  origin info:
    place:
      place term: xx
    date issued: 2016
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 6
  abstract: This work examines the variation of longitudinal relaxation rate R1(= 1/T1) of the 19F-CF3-resonance of semifluorinated alkanes (SFAs) with oxygen tension (pO2), temperature (T) and pH in vitro. Contrary to their related perfluorocarbons (PFCs), SFA are amphiphilic and facilitate stable emulsions, a prerequisite for clinical use. A linear relationship between R1 and pO2 was confirmed for the observed SFAs at different temperatures. Using a standard saturation recovery sequence, T1 has been successfully measured using fluorine 19F-MRI with a self-constructed birdcage resonator at 9.4 T. A calibration curve to calculate pO2 depending on T and R1 was found for each SFA used. In contrast to the commonly used PFC, SFAs are less sensitive to changes in pO2, but more sensitive to changes in temperature. The influence of pH to R1 was found to be negligible.
  note: Stefan Kegel, Jorge Chacon-Caldera, Charalambos Tsagogiorgas, Bastian Theisinger, Gerhard Glatting and Lothar R. Schad
  note: Gesehen am 30.10.2019
  note: Die Zahl 19 im Titel ist hochgestellt
  note: Published online 24 November 2015
  note: 2015
  subject:
    topic: 19F
  subject:
    topic: alkane
  subject:
    topic: fluorine
  subject:
    topic: hexafluorobenzene
  subject:
    topic: hypoxia
  subject:
    topic: MRI
  subject:
    topic: oxygen
  subject:
    topic: relaxation
  subject:
    topic: semifluorinated
  subject:
    topic: semifluorinated alkanes
  classification: 33
  related item:
    origin info:
      publisher: 2015
  related item:
    title info:
      title: Artificial cells, nanomedicine, and biotechnology
    name:
      name part: 19F oximetry with semifluorinated alkanes
    origin info:
      publisher: Abingdon : Taylor & Francis Group, 2013
    physical description:
      extent: Online-Ressource
    identifier: 2169-141X
    identifier: (DE-627)742222489
    identifier: (DE-600)2711415-6
    identifier: (DE-576)381271765
    part:
      text: 44(2016), 8, Seite 1861-1866
  related item:
    name:
      name part: 19F oximetry with semifluorinated alkanes
    part:
      text: volume:44
    part:
      text: year:2016
    part:
      text: number:8
    part:
      text: pages:1861-1866
    part:
      text: extent:6
  identifier: https://doi.org/10.3109/21691401.2015.1111228
  record info:
    record content source: DE-627
    record creation date: 191030
    record change date: 20230427033306.0
    record identifier: 1680728199
    language of cataloging:
      language term: ger