Artificial urinary sphincter cuff size predicts outcome in male patients treated for stress incontinence: results of a large central european multicenter cohort study

Purpose: The aim was to study the correlation between cuff size and outcome after implantation of an AMS 800 artificial urinary sphincter. Methods: A total of 473 male patients with an AMS 800 sphincter implanted between 2012 and 2014 were analyzed in a retrospective multicenter cohort study perfor...

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Main Authors: Queißert, Fabian (Author) , Nyarangi-Dix, Joanne (Author)
Format: Article (Journal)
Language:English
Published: September 30, 2019
In: International neurourology journal
Year: 2019, Volume: 23, Issue: 3, Pages: 219-225
ISSN:2093-6931
DOI:10.5213/inj.1938032.016
Online Access:Verlag, Volltext: https://doi.org/10.5213/inj.1938032.016
Verlag: http://www.einj.org/journal/view.php?doi=10.5213/inj.1938032.016
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Author Notes:Fabian Queissert, Tanja Huesch, Alexander Kretschmer, Ralf Anding, Martin Kurosch, Ruth Kirschner-Hermanns, Tobias Pottek, Roberto Olianas, Alexander Friedl, Jesco Pfitzenmaier, Carsten M. Naumann, Carola Wotzka, Joanne Nyarangi-Dix, Torben Hoffmann, Edwin Herrmann, Alice Obaje, Achim Rose, Roland Homberg, Rudi Abdunnur, Hagen Loertzer, Ricarda M. Bauer, Axel Haferkamp, Andres J. Schrader ; Debates on Male Incontinence (DOMINO)-Project

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520 |a  Purpose: The aim was to study the correlation between cuff size and outcome after implantation of an AMS 800 artificial urinary sphincter. Methods: A total of 473 male patients with an AMS 800 sphincter implanted between 2012 and 2014 were analyzed in a retrospective multicenter cohort study performed as part of the Central European Debates on Male Incontinence (DOMINO) Project. Results: Single cuffs were implanted in 54.5% and double cuffs in 45.5% of the patients. The cuffs used had a median circumference of 4.5 cm. Within a median follow of 18 months, urethral erosion occurred in 12.8% of the cases and was associated significantly more often with small cuff sizes (P<0.001). Multivariate analysis showed that, apart from cuff size (P=0.03), prior irradiation (P<0.001) and the penoscrotal approach (P=0.036) were associated with an increased erosion rate. Continence rate tended to be highest with median cuff sizes (4–5.5 cm). Conclusions: Apart from irradiation and the penoscrotal approach, small cuff size is a risk factor for urethral erosion. Results are best with cuff sizes of 4.5–5.5 cm. 
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