An innovative surgical technique for subretinal transplantation of human embryonic stem cell-derived retinal pigmented epithelium in Yucatan mini pigs: preliminary results
Ophthalmic Surgery, Lasers and Imaging Retina | BACKGROUND AND OBJECTIVE: - To develop a safe and efficient surgical procedure for subretinal implantation into porcine eyes of a human embryonic stem cell-derived retinal pigmented epithelium (hESC-RPE) monolayer seeded onto a Parylene-C scaffold. Thi...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
April 13, 2016
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| In: |
Ophthalmic surgery, lasers & imaging retina
Year: 2016, Volume: 47, Issue: 4, Pages: 342-351 |
| ISSN: | 2325-8179 |
| DOI: | 10.3928/23258160-20160324-07 |
| Online Access: | Verlag, Volltext: https://doi.org/10.3928/23258160-20160324-07 Verlag, Volltext: https://www.healio.com/ophthalmology/journals/osli/2016-4-47-4/{8bdc9678-51bb-42a4-80e3-ed848b445501}/an-innovative-surgical-technique-for-subretinal-transplantation-of-human-embryonic-stem-cell-derived-retinal-pigmented-epithelium-in-yucatan-mini-pigs-preliminary-results 
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| Author Notes: | Rodrigo A. Brant Fernandes, MD; Michael Janusz Koss, MD; Paulo Falabella, Francisco Rosa Stefanini, Mauricio Maia, Bruno Diniz, MD; Ramiro Ribeiro, MD; Yuntao Hu, MD; David Hinton, MD, PhD; Dennis O. Clegg, Gerald Chader, PhD; Mark S. Humayun, MD, PhD |
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| 520 | |a Ophthalmic Surgery, Lasers and Imaging Retina | BACKGROUND AND OBJECTIVE: - To develop a safe and efficient surgical procedure for subretinal implantation into porcine eyes of a human embryonic stem cell-derived retinal pigmented epithelium (hESC-RPE) monolayer seeded onto a Parylene-C scaffold. This implant is referred to as CPCB-RPE1. - - MATERIALS AND METHODS: - Ultrathin Parylene-C scaffolds were seeded with hESC-RPE and surgically implanted into | ||
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