Hdac1 regulates differentiation of bipotent liver progenitor cells during regeneration via Sox9b and Cdk8
Upon liver injury in which hepatocyte proliferation is compromised, liver progenitor cells (LPCs), derived from biliary epithelial cells (BECs), differentiate into hepatocytes. Little is known about the mechanisms of LPC differentiation. We used zebrafish and mouse models of liver injury to study th...
Gespeichert in:
| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
26 September 2018
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| In: |
Gastroenterology
Year: 2019, Jahrgang: 156, Heft: 1, Pages: 187-202.e14 |
| ISSN: | 1528-0012 |
| DOI: | 10.1053/j.gastro.2018.09.039 |
| Online-Zugang: | Resolving-System, Volltext: https://doi.org/10.1053/j.gastro.2018.09.039 Verlag: http://www.sciencedirect.com/science/article/pii/S0016508518350339 
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| Verfasserangaben: | Sungjin Ko, Jacquelyn O. Russell, Jianmin Tian, Ce Gao, Makoto Kobayashi, Rilu Feng, Xiaodong Yuan, Chen Shao, Huiguo Ding, Minakshi Poddar, Sucha Singh, Joseph Locker, Hong-Lei Weng, Satdarshan P. Monga, and Donghun Shin |
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| 520 | |a Upon liver injury in which hepatocyte proliferation is compromised, liver progenitor cells (LPCs), derived from biliary epithelial cells (BECs), differentiate into hepatocytes. Little is known about the mechanisms of LPC differentiation. We used zebrafish and mouse models of liver injury to study the mechanisms. | ||
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