Principles and applications of optogenetics in developmental biology

Skip to Next Section - The development of multicellular organisms is controlled by highly dynamic molecular and cellular processes organized in spatially restricted patterns. Recent advances in optogenetics are allowing protein function to be controlled with the precision of a pulse of laser light i...

Full description

Saved in:
Bibliographic Details
Main Authors: Krüger, Daniel (Author) , Izquierdo, Emiliano (Author) , Viswanathan, Ranjith (Author) , Hartmann, Jonas (Author) , Cartes, Cristina Pallares (Author) , Renzis, Stefano De (Author)
Format: Article (Journal)
Language:English
Published: 22 October 2019
In: Development
Year: 2019, Volume: 146, Issue: 20
ISSN:1477-9129
DOI:10.1242/dev.175067
Online Access:Verlag, Volltext: https://doi.org/10.1242/dev.175067
Verlag, Volltext: https://dev.biologists.org/content/146/20/dev175067
Get full text
Author Notes:Daniel Krueger, Emiliano Izquierdo, Ranjith Viswanathan, Jonas Hartmann, Cristina Pallares Cartes and Stefano De Renzis
Description
Summary:Skip to Next Section - The development of multicellular organisms is controlled by highly dynamic molecular and cellular processes organized in spatially restricted patterns. Recent advances in optogenetics are allowing protein function to be controlled with the precision of a pulse of laser light in vivo, providing a powerful new tool to perturb developmental processes at a wide range of spatiotemporal scales. In this Primer, we describe the most commonly used optogenetic tools, their application in developmental biology and in the nascent field of synthetic morphogenesis.
Item Description:Gesehen am 21.11.2019
Physical Description:Online Resource
ISSN:1477-9129
DOI:10.1242/dev.175067