Choline chloride/ urea as mild media for the synthesis of the chromonyl amidodiester fragments and succinimide derivatives
A simple, green protocol has been accomplished for the synthesis of amidoesters 5 a-k in choline chloride/urea (1:2) through multicomponent reaction of 3-formyl chromone, Meldrum's acid, isocyanides and primary alcohols via a domino reaction. Carrying out the reaction using trifluoroethanol led...
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| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
16 August 2019
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| In: |
ChemistrySelect
Year: 2019, Jahrgang: 4, Heft: 31, Pages: 9074-9078 |
| ISSN: | 2365-6549 |
| DOI: | 10.1002/slct.201901893 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1002/slct.201901893 Verlag: https://onlinelibrary.wiley.com/doi/abs/10.1002/slct.201901893 
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| Verfasserangaben: | Hoda Jamaati, Saeed Balalaie, Maryam Kazemi Miraki, Frank Rominger, and Hamid Reza Bijanzadeh |
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| 520 | |a A simple, green protocol has been accomplished for the synthesis of amidoesters 5 a-k in choline chloride/urea (1:2) through multicomponent reaction of 3-formyl chromone, Meldrum's acid, isocyanides and primary alcohols via a domino reaction. Carrying out the reaction using trifluoroethanol led to succinimide derivatives 6 a-d. Easy work-up, selectivity, and good to excellent yields are the advantages of this protocol. | ||
| 650 | 4 | |a Choline Chloride/urea (1:2) | |
| 650 | 4 | |a Chromonyl amidoester | |
| 650 | 4 | |a Deep Eutectic Solvent | |
| 650 | 4 | |a Domino reaction | |
| 650 | 4 | |a Succinimide | |
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