Primary human hepatocytes are protected against complement by multiple regulators

Inflammatory liver disorders are often associated with a potentially tissue damaging complement activation directly at the main site of complement protein synthesis. As hepatocytes may be the primary target of complement attack, we investigated the expression and protective capacity of soluble and m...

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Bibliographic Details
Main Authors: Halme, Jarkko (Author) , Sachse, Michael (Author) , Vogel, Heiko (Author) , Giese, Thomas (Author) , Klar, Ernst (Author) , Kirschfink, Michael (Author)
Format: Article (Journal)
Language:English
Published: 14 May 2009
In: Molecular immunology
Year: 2009, Volume: 46, Issue: 11/12, Pages: 2284-2289
ISSN:1872-9142
DOI:10.1016/j.molimm.2009.04.005
Online Access:Verlag, Volltext: https://doi.org/10.1016/j.molimm.2009.04.005
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0161589009001746
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Author Notes:Jarkko Halme, Michael Sachse, Heiko Vogel, Thomas Giese, Ernst Klar, Michael Kirschfink