An international perspective on the tools and concepts for effluent toxicity assessments in the context of animal alternatives: reduction in vertebrate use

Since the 1940s, effluent toxicity testing has been used to assess potential ecological impacts of effluents and help determine necessary treatment options for environmental protection prior to release. Strategic combinations of toxicity tests, analytical tools, and biological monitoring have been d...

Full description

Saved in:
Bibliographic Details
Main Authors: Norberg-King, Teresa J. (Author) , Braunbeck, Thomas (Author)
Format: Article (Journal)
Language:English
Published: 25 October 2018
In: Environmental toxicology and chemistry
Year: 2018, Volume: 37, Issue: 11, Pages: 2745-2757
ISSN:1552-8618
DOI:10.1002/etc.4259
Online Access:Verlag, Volltext: https://doi.org/10.1002/etc.4259
Verlag, Volltext: https://setac.onlinelibrary.wiley.com/doi/abs/10.1002/etc.4259
Get full text
Author Notes:Teresa J. Norberg‐King, Michelle R. Embry, Scott E. Belanger, Thomas Braunbeck, Joshua D. Butler, Phil B. Dorn, Brianna Farr, Patrick D. Guiney, Sarah A. Hughes, Marlo Jeffries, Romain Journel, Marc Lèonard, Mark McMaster, James T. Oris, Kathy Ryder, Helmut Segner, Thomas Senac, Glen Van Der Kraak, Graham Whale, and Peter Wilson

MARC

LEADER 00000caa a2200000 c 4500
001 1684994608
003 DE-627
005 20230427200307.0
007 cr uuu---uuuuu
008 191210s2018 xx |||||o 00| ||eng c
024 7 |a 10.1002/etc.4259  |2 doi 
035 |a (DE-627)1684994608 
035 |a (DE-599)KXP1684994608 
035 |a (OCoLC)1341280831 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 32  |2 sdnb 
100 1 |a Norberg-King, Teresa J.  |e VerfasserIn  |0 (DE-588)1201392187  |0 (DE-627)1684996023  |4 aut 
245 1 3 |a An international perspective on the tools and concepts for effluent toxicity assessments in the context of animal alternatives  |b reduction in vertebrate use  |c Teresa J. Norberg‐King, Michelle R. Embry, Scott E. Belanger, Thomas Braunbeck, Joshua D. Butler, Phil B. Dorn, Brianna Farr, Patrick D. Guiney, Sarah A. Hughes, Marlo Jeffries, Romain Journel, Marc Lèonard, Mark McMaster, James T. Oris, Kathy Ryder, Helmut Segner, Thomas Senac, Glen Van Der Kraak, Graham Whale, and Peter Wilson 
264 1 |c 25 October 2018 
300 |b Illustrationen 
300 |a 13 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 10.12.2019 
520 |a Since the 1940s, effluent toxicity testing has been used to assess potential ecological impacts of effluents and help determine necessary treatment options for environmental protection prior to release. Strategic combinations of toxicity tests, analytical tools, and biological monitoring have been developed. Because the number of vertebrates utilized in effluent testing is thought to be much greater than that used for individual chemical testing, there is a new need to develop strategies to reduce the numbers of vertebrates (i.e., fish) used. This need will become more critical as developing nations begin to use vertebrates in toxicity tests to assess effluent quality. A workshop was held to 1) assess the state of science in effluent toxicity testing globally; 2) determine current practices of regulators, industry, private laboratories, and academia; and 3) explore alternatives to vertebrate (fish) testing options and the inclusion of modified/new methods and approaches in the regulatory environment. No single approach was identified, because of a range of factors including regulatory concerns, validity criteria, and wider acceptability of alternatives. However, a suite of strategies in a weight-of-evidence approach would provide the flexibility to meet the needs of the environment, regulators, and the regulated community; and this “toolbox” approach would also support reduced reliance on in vivo fish tests. The present Focus article provides a brief overview of wastewater regulation and effluent testing approaches. Alternative methodologies under development and some of the limitations and barriers to regulatory approaches that can be selected to suit individual country and regional requirements are described and discussed 
650 4 |a Animal alternatives 
650 4 |a Effluent testing 
650 4 |a Regulation 
650 4 |a Toxicity testing 
650 4 |a Wastewater 
650 4 |a Weight of evidence 
700 1 |a Braunbeck, Thomas  |e VerfasserIn  |0 (DE-588)106835819X  |0 (DE-627)82017839X  |0 (DE-576)165906731  |4 aut 
773 0 8 |i Enthalten in  |t Environmental toxicology and chemistry  |d [Oxford] : Oxford University Press on behalf of the Society of Environmental Toxicology and Chemistry, 1982  |g 37(2018), 11, Seite 2745-2757  |h Online-Ressource  |w (DE-627)324487290  |w (DE-600)2027441-5  |w (DE-576)117978655  |x 1552-8618  |7 nnas  |a An international perspective on the tools and concepts for effluent toxicity assessments in the context of animal alternatives reduction in vertebrate use 
773 1 8 |g volume:37  |g year:2018  |g number:11  |g pages:2745-2757  |g extent:13  |a An international perspective on the tools and concepts for effluent toxicity assessments in the context of animal alternatives reduction in vertebrate use 
856 4 0 |u https://doi.org/10.1002/etc.4259  |x Verlag  |x Resolving-System  |3 Volltext 
856 4 0 |u https://setac.onlinelibrary.wiley.com/doi/abs/10.1002/etc.4259  |x Verlag  |3 Volltext 
951 |a AR 
992 |a 20191210 
993 |a Article 
994 |a 2018 
998 |g 106835819X  |a Braunbeck, Thomas  |m 106835819X:Braunbeck, Thomas  |d 700000  |d 721000  |e 700000PB106835819X  |e 721000PB106835819X  |k 0/700000/  |k 1/700000/721000/  |p 4 
999 |a KXP-PPN1684994608  |e 3563219699 
BIB |a Y 
SER |a journal 
JSO |a {"type":{"bibl":"article-journal","media":"Online-Ressource"},"note":["Gesehen am 10.12.2019"],"recId":"1684994608","person":[{"display":"Norberg-King, Teresa J.","role":"aut","roleDisplay":"VerfasserIn","given":"Teresa J.","family":"Norberg-King"},{"display":"Braunbeck, Thomas","given":"Thomas","role":"aut","roleDisplay":"VerfasserIn","family":"Braunbeck"}],"language":["eng"],"name":{"displayForm":["Teresa J. Norberg‐King, Michelle R. Embry, Scott E. Belanger, Thomas Braunbeck, Joshua D. Butler, Phil B. Dorn, Brianna Farr, Patrick D. Guiney, Sarah A. Hughes, Marlo Jeffries, Romain Journel, Marc Lèonard, Mark McMaster, James T. Oris, Kathy Ryder, Helmut Segner, Thomas Senac, Glen Van Der Kraak, Graham Whale, and Peter Wilson"]},"origin":[{"dateIssuedKey":"2018","dateIssuedDisp":"25 October 2018"}],"id":{"eki":["1684994608"],"doi":["10.1002/etc.4259"]},"physDesc":[{"extent":"13 S.","noteIll":"Illustrationen"}],"relHost":[{"id":{"eki":["324487290"],"zdb":["2027441-5"],"issn":["1552-8618"],"doi":["10.1002/(ISSN)1552-8618"]},"titleAlt":[{"title":"ET & C online"},{"title":"ET and C online"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"pubHistory":["1.1982 -"],"note":["Gesehen am 13.03.25"],"recId":"324487290","part":{"text":"37(2018), 11, Seite 2745-2757","pages":"2745-2757","year":"2018","extent":"13","volume":"37","issue":"11"},"language":["eng"],"disp":"An international perspective on the tools and concepts for effluent toxicity assessments in the context of animal alternatives reduction in vertebrate useEnvironmental toxicology and chemistry","origin":[{"dateIssuedKey":"2025","publisherPlace":"[Oxford] ; [Oxford] ; Lawrence, KS","publisher":"Oxford University Press on behalf of the Society of Environmental Toxicology and Chemistry ; Pergamon ; SETAC","dateIssuedDisp":"2025-"}],"physDesc":[{"extent":"Online-Ressource"}],"title":[{"subtitle":"ET & C online ; a monthly publication of the Society of Environmental Toxicology and Chemistry","title_sort":"Environmental toxicology and chemistry","title":"Environmental toxicology and chemistry"}]}],"title":[{"title_sort":"international perspective on the tools and concepts for effluent toxicity assessments in the context of animal alternatives","title":"An international perspective on the tools and concepts for effluent toxicity assessments in the context of animal alternatives","subtitle":"reduction in vertebrate use"}]} 
SRT |a NORBERGKININTERNATIO2520