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Prophylactic onlay reinforcement with absorbable mesh (polyglactin) is associated with less early wound complications after kidney transplantation: a preliminary study

Incidence of wound complications after kidney transplantation (KTx) is still considerable. Here, we report the impact of prophylactic absorbable polyglactin (Vicryl®) mesh reinforcement on the incidence of short-term post-KTx wound complications. Sixty-nine patients were analyzed; 23 with and 46 wit...

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Main Authors: Michalski, Christoph (Author) , Mohammadi, Sara (Author) , Khajeh, Elias (Author) , Ghamarnejad, Omid (Author) , Sabagh, Mohammad Sadegh (Author) , Pianka, Frank (Author) , Golriz, Mohammad (Author) , Kulu, Yakup (Author) , Kallinowski, Friedrich (Author) , Zeier, Martin (Author) , Morath, Christian (Author) , Diener, Markus K. (Author) , Büchler, Markus W. (Author) , Mehrabi, Arianeb (Author)
Format: Article (Journal)
Language:English
Published: 2020
In: Journal of biomedical materials research. Part B, Applied biomaterials
Year: 2020, Volume: 108, Issue: 1, Pages: 67-72
ISSN:1552-4981
DOI:10.1002/jbm.b.34366
Online Access:Verlag, Volltext: https://doi.org/10.1002/jbm.b.34366
Verlag, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/jbm.b.34366
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Author Notes:Christoph W. Michalski, Sara Mohammadi, Elias Khajeh, Omid Ghamarnejad, Mohammadsadegh Sabagh, Frank Pianka, Mohammad Golriz, Yakup Kulu, Friedrich Kallinowski, Martin Zeier, Christian Morath, Markus K. Diener, Markus W. Büchler, Arianeb Mehrabi

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520 |a Incidence of wound complications after kidney transplantation (KTx) is still considerable. Here, we report the impact of prophylactic absorbable polyglactin (Vicryl®) mesh reinforcement on the incidence of short-term post-KTx wound complications. Sixty-nine patients were analyzed; 23 with and 46 without preventive onlay mesh reinforcement. Surgical site infections (SSI) were seen in six (26%) patients in the mesh group and in 17 (37%) patients in no-mesh group. A lower, but not statistically significant, rate of early postoperative wound complications occurred in the mesh group. Wound complications were observed in seven (30%) patients in the mesh group and in 23 (50%) patients in the no-mesh group. There was no association between mesh placement and SSI incidence (odds ratios [OR] 0.60, 95% confidence interval [CI] 0.20-1.82, p = 0.369) and wound complications (OR 0.44, 95% CI 0.15-1.26, p = 0.126). Therefore, we conclude that mesh reinforcement does not increase the risk of SSI and overall wound complications. Long-term outcomes have to be evaluated in a randomized trial setting. © 2019 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 108B:67-72, 2020. 
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