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Web-based design and analysis tools for CRISPR base editing

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As a result of its simplicity and high efficiency, the CRISPR-Cas system has been widely used as a genome editing tool. Recently, CRISPR base editors, which consist of deactivated Cas9 (dCas9) or Cas9 nickase (nCas9) linked with a cytidine or a guanine deaminase, have been developed. Base editing to...

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Main Authors: Hwang, Gue-Ho (Author) , Park, Jeongbin (Author) , Eils, Roland (Author)
Format: Article (Journal)
Language:English
Published: 27 December 2018
In: BMC bioinformatics
Year: 2018, Volume: 19
ISSN:1471-2105
DOI:10.1186/s12859-018-2585-4
Online Access:Verlag, Volltext: https://doi.org/10.1186/s12859-018-2585-4
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Author Notes:Gue-Ho Hwang, Jeongbin Park, Kayeong Lim, Sunghyun Kim, Jihyeon Yu, Eunchong Yu, Sang-Tae Kim, Roland Eils, Jin-Soo Kim, Sangsu Bae
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Web-based design and analysis tools for CRISPR base editing by Hwang, Gue-Ho (Author) , Park, Jeongbin (Author) , Eils, Roland (Author) , Kim, Jin-Soo (Author) , Bae, Sangsu (Author) ,

BioMed Central$pSpringer 8 Feb. 2019 Universitätsbibliothek Heidelberg 8 Feb. 2019

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