Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours
Paediatric solid tumours are known to be divergent from adult malignancies. This Review describes the molecular landscape of paediatric solid tumours, the therapeutic vulnerabilities that can be targeted and the preclinical models available to test the efficacy of investigational drugs with a view t...
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| Hauptverfasser: | , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
12 July 2019
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| In: |
Nature reviews. Cancer
Year: 2019, Jahrgang: 19, Heft: 8, Pages: 420-438 |
| ISSN: | 1474-1768 |
| DOI: | 10.1038/s41568-019-0169-x |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1038/s41568-019-0169-x Verlag, Volltext: https://www.nature.com/articles/s41568-019-0169-x 
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| Verfasserangaben: | David T.W. Jones, Ana Banito, Thomas G.P. Grünewald, Michelle Haber, Natalie Jäger, Marcel Kool, Till Milde, Jan J. Molenaar, Arash Nabbi, Trevor J. Pugh, Gudrun Schleiermacher, Malcolm A. Smith, Frank Westermann and Stefan M. Pfister |
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