Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations

Key Points. RNA-seq analysis of CD34+ cells identifies novel aberrantly spliced genes and dysregulated pathways in splicing factor mutant MDS.Aberrantly splice

Saved in:

Bibliographic Details
Main Authors:	Pellagatti, Andrea (Author) , Radujković, Aleksandar (Author) , Horn, Patrick (Author) , Ho, Anthony Dick (Author) , Luft, Thomas (Author)
Format:	Article (Journal)
Language:	English
Published:	20 September 2018
In:	Blood Year: 2018, Volume: 132, Issue: 12, Pages: 1225-1240
ISSN:	1528-0020
DOI:	10.1182/blood-2018-04-843771
Online Access:	Verlag, Volltext: https://doi.org/10.1182/blood-2018-04-843771
Author Notes:	Andrea Pellagatti, Richard N. Armstrong, Violetta Steeples, Eshita Sharma, Emmanouela Repapi, Shalini Singh, Andrea Sanchi, Aleksandar Radujkovic, Patrick Horn, Hamid Dolatshad, Swagata Roy, John Broxholme, Helen Lockstone, Stephen Taylor, Aristoteles Giagounidis, Paresh Vyas, Anna Schuh, Angela Hamblin, Elli Papaemmanuil, Sally Killick, Luca Malcovati, Marco L. Hennrich, Anne-Claude Gavin, Anthony D. Ho, Thomas Luft, Eva Hellström-Lindberg, Mario Cazzola, Christopher W. J. Smith, Stephen Smith, and Jacqueline Boultwood

Description
Summary:	Key Points. RNA-seq analysis of CD34+ cells identifies novel aberrantly spliced genes and dysregulated pathways in splicing factor mutant MDS.Aberrantly splice
Item Description:	Gesehen am 07.02.2020
Physical Description:	Online Resource
ISSN:	1528-0020
DOI:	10.1182/blood-2018-04-843771